Product References — Human Serum

Single Donor Human Complement Serum from Innovative Research was used in the following study:   Cytoprotective IgG Antibodies in Sera from a Subset of Patients with AQP4‑IgG Seropositive Neuromyelitis Optica Spectrum Disorder LukmaneeTradtrantip, Michael R. Yeaman & A. S. Verkman Scientific Reports November 9, 2021 Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disorder that attacks the central nervous system and can cause demyelination in the optic nerve, spinal cord, and brain, and potentially cause further neurological deficits. Over 70% of patients suffering from NMOSD are seropositive for IgG autoantibodies which target extracellular epitopes of astrocyte water channel aquaporin-4 (AQP4),...

Single Donor Human Serum Off The Clot from Innovative Research was used in the following study:   Integrated Dielectrophoretic and Impedimetric Biosensor Provides a Template for Universal Biomarker Sensing in Clinical Samples Logeeshan Velmanickam, Vidura Jayasooriya, Dharmakeerthi Nawarathna Electrophoresis January 20, 2021 The use of circulating biomarker tests is common in the screening and diagnosis of various diseases and infections. These tests commonly target biomarkers such as DNA, miRNA, and proteins, however, these different molecules all require different testing procedures and assays which increase the time and costs associated with diagnosis. Miniaturized testing devices have been utilized as a faster...

Pooled Human Serum Off The Clot from Innovative Research was used in the following study:   Two Distinct Genotypes of KPC-2-Producing Klebsiella pneumoniae Isolates from South Korea Jee Hong Kim, Yun Young Cho, Ji Young Choi, Yu Mi Wi, and Kwan Soo Ko Antibiotics July 26, 2021 In South Korea in 2010, the emergence of carbapenemase-producing Gram-negative bacteria caused serious therapeutic concern and challenges. In particular, Klebsiella pneumoniae, which produces K. pneumoniae carbapenemase (KPC), has proven to be one of the most threatening of these carbapenem resistance determinants in clinical settings. This is because K. pneumoniae is difficult to control...

Pooled Human Serum Off The Clot and Pooled Human Urine from Innovative Research were used in the following study:   Development of Diagnostic Immunoassays for Tularemia and Leptospirosis Emily E. Hannah, Dr. David P. AuCoin University of Nevada, Reno May, 2021 Bacteria strains Francisella tularensis and Leptospira are the causes for tularemia and leptospirosis infections, respectively. Tularemia refers to a range of symptoms caused by Francisella tularensis that can be dangerous, and potentially fatal. Tularemia also refers to a variety of symptoms that can range from mild to severe, and initially presents itself through symptoms like head and body pain...

Pooled Human Charcoal Dextran Stripped Serum from Innovative Research was used in the following study:   Schisandrol A Exhibits Estrogenic Activity via Estrogen Receptor α-Dependent Signaling Pathway in Estrogen Receptor-Positive Breast Cancer Cells Dahae Lee, Young-Mi Kim, Young-Won Chin, and Ki Sung Kang Pharmaceutics July 15, 2021 Estrogen is a naturally occurring steroid hormone responsible for the development of the female reproductive system; the effects of estrogen are exhibited once estrogen binds to the estrogen receptor (ER) in a cell. Within the cell nucleus, the ERs bind to DNA and promotes the development of both normal breast cells and tumorous...