Product References — Animal Whole Blood

Biomimetic Anisotropic Polymeric Nanoparticles Coated with Red Blood Cell Membranes for Enhanced Circulation and Toxin Removal

Posted by Adam Awdish on

Biomimetic Anisotropic Polymeric Nanoparticles Coated with Red Blood Cell Membranes for Enhanced Circulation and Toxin Removal

Innovative Grade US Origin Mouse CD1 Whole Blood from Innovative Research was used in the following study:   Biomimetic Anisotropic Polymeric Nanoparticles Coated with Red Blood Cell Membranes for Enhanced Circulation and Toxin Removal Elana Ben-Akiva, Randall A. Meyer, Hongzhe Yu, Jonathan T. Smith, Drew M. Pardoll, Jordan J. Green Science Advances April 15, 2020 Therapeutic devices based on biomaterials can have enhanced function due to mimicry of naturally occurring structures. Cell membrane coatings can be used to mimic the functionality of various cell types, enhancing delivery properties, and extending the half-life of blood circulation. However, previous studies have used...

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Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal

Posted by Corey Marcath on

Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal

Innovative Grade US Origin Sheep Whole Blood Defibrinated from Innovative Research was used in the following study:   Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal BRIAN Y. CHANG and STEVEN P. KELLER Biomedical Engineering Society 2/1/2020 “Extracorporeal CO2 removal is a highly promising support therapy for patients with hypercapnic respiratory failure but whose clinical implementation and patient benefit is hampered by high cost and highly specialized expertise required for safe use. Current approaches target removal of the gaseous CO2 dissolved in blood which limits their ease of clinical use as high blood...

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Mathematical modeling of the “inoculum effect”: six applicable models and the MIC advancement point concept

Posted by Corey Marcath on

Mathematical modeling of the “inoculum effect”: six applicable models and the MIC advancement point concept

Innovative Grade US Origin Horse Whole Blood Lysed from Innovative Research was used in the following study:   Mathematical modeling of the “inoculum effect”: six applicable models and the MIC advancement point concept Jessica R. Salas, Majid Jaberi-Douraki, Xuesong Wen, Victoriya V. Volkova FEMS Microbiology Letters 21 January 2020 “…Antimicrobial treatment regimens against bacterial pathogens are designed using the drug’s minimum inhibitory concentration (MIC) measured at the bacterial density of 5.7 log10(colonyforming units (CFU)/mL) in vitro. However, MIC changes with pathogen density, which varies among infectious diseases and during treatment. Incorporating this into treatment design requires realistic mathematical models of...

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Recognition of specific sialoglycan structures by oral streptococci impacts the severity of endocardial infection

Posted by Corey Marcath on

Recognition of specific sialoglycan structures by oral streptococci impacts the severity of endocardial infection

Innovative Grade US Origin Rat Sprague Dawley Whole Blood from Innovative Research was used in the following study:   Recognition of specific sialoglycan structures by oral streptococci impacts the severity of endocardial infection Barbara A. Bensing, Liang Li, Olga Yakovenko, Maurice Wong, Karen N. Barnard, T. M. Iverson, Carlito B. Lebrilla, Colin R. Parrish, Wendy E. Thomas, Yan Xiong, Paul M. Sullam PLOS Pathogens 2019 Jun 24 “…Streptococcus gordonii and Streptococcus sanguinis are primary colonizers of the tooth surface. Although generally non-pathogenic in the oral environment, they are a frequent cause of infective endocarditis. Both streptococcal species express a serine-rich...

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Population history with invasive predators predicts innate immune function response to early life glucocorticoid exposure

Posted by Leanne Kodsmann on

Population history with invasive predators predicts innate immune function response to early life glucocorticoid exposure

Sheep Red Blood Cells from Innovative Research was used in the following study:   Population history with invasive predators predicts innate immune function response to early life glucocorticoid exposure Gail L. McCormick, Travis R. Robbins, Sonia A. Cavigelli, Tracy Langkilde Journal of Experimental Biology February 2019 "... This assay measures ability of lizard plasma to hold sheep red blood cells (SRBC) in suspension in vitro. We first measured baseline hemagglutination, which is primarily driven by natural antibodies. SRBC (Innovative Research, Novi, MI, USA) were washed with phosphate buffered saline (PBS) and brought to a 2% solution with PBS. Plasma (25...

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