Product References

Human Factor II (Prothrombin) Purified, Human Fibrinogen Purified, and Rabbit Anti Mouse/Rat Fibrinogen Polyclonal Affinity Purified from Innovative Research were used in the following study:   Contribution of Coagulases towards Staphylococcus aureus Disease and Protective Immunity Alice G. Cheng, Molly McAdow, Hwan K. Kim, Taeok Bae, Dominique M. Missiakas, Olaf Schneewind PLOS Pathogens August 5, 2010 Staphylococcus aureus is a bacterium responsible for many common infections, including bacteremia, pneumonia, soft tissue infections, and septic arthritis among others. There remains no known way to gain protective immunity against S. aureus diseases, and researchers continue to investigate options for an effective vaccine....

Pooled Human Serum Off The Clot from Innovative Research was used in the following study:   Rapid Detection of an Ebola Biomarker with Optical Microring Resonators Abraham J. Qavi, Krista Meserve, M. Javad Aman, Hong Vu, Larry Zeitlin, John M. Dye, Jeffrey W. Froude, Daisy W. Leung, Lan Yang, Frederick W. Holtsberg,, Ryan C. Bailey, and Gaya K. Amarasinghe Cell Reports June 20, 2022 RNA viruses are particularly effective at causing diseases in human populations, partially because of their ability to rapidly mutate. One of the deadliest types of RNA viruses, Filoviruses, are single-stranded, negative-sense RNA viruses; an example of...

Human Alpha 2 Antiplasmin Purified Lyophilized from Innovative Research was used in the following study:   Plasminogen and Plasmin can Bind to Human T Cells and Generate Truncated CCL21 that Increases Dendritic Cell Chemotactic Responses Evert J. Loef, Hilary M. Sheppard, Nigel P. Birch, Rod Dunbar Journal of Biological Chemistry June 9, 2022 Plasmin, a broad-spectrum protease that is highly regulated, is formed from plasminogen. This normally occurs in the blood, as plasminogen is found in high concentrations in circulation where it’s converted to plasmin by plasminogen activators. There are also high levels of α2-antiplasmin in circulation, which is a...

Human Total Factor XII ELISA Kit from Innovative Research was used in the following study:   Characterization of Congenital Factor XII Deficiency in Taiwanese Patients: Identification of One Novel and One Common Mutation Sheng-Chieh Chou, Ching-Yeh Lin, Hsuan-Yu Lin, Chen-Hsueh Pai, Cheng-Ye Yu, Su-Feng Kuo, Jen-Shiou Lin, Po-Te Lin, Mei-Hua Hung, Han-Ni Hsieh, Hsiang-Chun Liu & Ming-Ching Shen International Journal of Hematology June 8, 2022 Factor XII (FXII) deficiency is a condition that results in prolonged activation time of thromboplastin without being linked to excessive bleeding, and roughly 2% of otherwise healthy blood donors are reported to be deficient in...

Mouse Non Swiss Albino Serum from Innovative Research was used in the following study:   Pre-Clinical In-Vitro Studies on Parameters Governing Immune Complex Formation Marie Fichter, Gesa Richter, Alexander Bepperling, and Paul Wassmann Pharmaceutics June 13, 2022 Biotherapeutics provide an opportunity to make huge advancements in medical treatments, however, their development is often challenged by undesirable or unexpected immunogenic events that present themselves in patients. This is characterized by the formation of anti-drug antibodies (ADAs), which, under certain conditions, may cause the formation of immune complexes (ICs) that can trigger cascades with effects on various cell types. Unfortunately, the connection...