Product References

Evaluation of Viscoelastic Properties, Blood Coagulation, and Cellular Responses of a Temperature-Sensitive Gel for Hemostatic Application

Posted by Corey Marcath on

Evaluation of Viscoelastic Properties, Blood Coagulation, and Cellular Responses of a Temperature-Sensitive Gel for Hemostatic Application

Single Donor Human Whole Blood from Innovative Research was used in the following study:   Evaluation of Viscoelastic Properties, Blood Coagulation, and Cellular Responses of a Temperature-Sensitive Gel for Hemostatic Application Joseph Jun, Reid C. Millican, Jennifer A. Sherwood, Bernabe S. Tucker, Vineeth M. Vijayan, Grant C. Alexander, Vinoy Thomas, Brigitta C. Brott, and Patrick T. J. Hwang ACS Applied Bio Materials 4/7/2020 “Hemorrhagic blood loss from traumatic injury is the leading cause of death in severe accidents and combat injuries. Treating and stopping blood loss in a timely and effective manner is essential for the survival of the patient…...

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Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics

Posted by Corey Marcath on

Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics

Innovative Grade US Origin Canine Beagle Plasma from Innovative Research was used in the following study:   Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E.Haefeli Journal of Pharmaceutical and Biomedical Analysis 27 March 2020 Bremelanotide (Vyleesi®) is an -melanocyte-stimulating hormone analog that was recently approved for the treatment of premenopausal hypoactive sexual desire disorder (HSDD; [1]). It is a cyclic heptapeptide (sequence: Ac-Nle-cyclo[Asp-His-d-PheArg-Trp-Lys]−OH) that is cyclized via amide bonding of the side chain carboxy-function of Asp to the amino group of the side...

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Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal

Posted by Corey Marcath on

Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal

Innovative Grade US Origin Sheep Whole Blood Defibrinated from Innovative Research was used in the following study:   Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal BRIAN Y. CHANG and STEVEN P. KELLER Biomedical Engineering Society 2/1/2020 “Extracorporeal CO2 removal is a highly promising support therapy for patients with hypercapnic respiratory failure but whose clinical implementation and patient benefit is hampered by high cost and highly specialized expertise required for safe use. Current approaches target removal of the gaseous CO2 dissolved in blood which limits their ease of clinical use as high blood...

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Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment

Posted by Corey Marcath on

Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment

Innovative Grade US Origin Rat Wistar Plasma from Innovative Research was used in the following study:   Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment Juliana G. Galvãoa, Raquel L. Santosa, Audrey R.S.T. Silvab, Jeferson S. Santosa, Amanda M.B. Costaa , Hardik Chandasanac, Valter V. Andrade-Netod, Eduardo Caio Torres-Santosd, Ana Amélia M. Liraa, Silvio Dolabellab, Ricardo Scherb, Peter E. Kimae, Hartmut Derendorfc, Rogéria S. Nunes European Journal of Pharmaceutical Sciences 1 July 2020 “Leishmaniasis are a group of neglected infectious diseases caused by protozoa of the genus Leishmania with distinct presentations. The available leishmaniasis treatment...

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Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins

Posted by Corey Marcath on

Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins

Pooled Human Urine and Pooled Human Serum Off The Clot from Innovative Research was used in the following study:   Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins Alex J. Rai Kevin A. Schug, Katarína Maráková Journal of Separation Science 2/7/2020 “In biological systems, variable protein expression is a crucial marker for numerous diseases, including cancer. The vast majority of liquid chromatography–triple quadrupole mass spectrometry-based quantitative protein assays use bottom-up methodologies, where proteins are subjected to proteolytic cleavage prior to analysis. …As biological...

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