Product References

Presence of Round Cells Proteins do not Interfere with Identification of Human Sperm Proteins from Frozen Semen Samples by LC-MS/MS

Posted by Leanne Kodsmann on

Presence of Round Cells Proteins do not Interfere with Identification of Human Sperm Proteins from Frozen Semen Samples by LC-MS/MS

Single Donor Human Buffy Coats Leukocytes from Innovative Research was used in the following study:   Presence of Round Cells Proteins do not Interfere with Identification of Human Sperm Proteins from Frozen Semen Samples by LC-MS/MS Manesh Kumar Panner Selvam, Ashok Agarwal, Tânia R. Dias, Ana D. Martins and Luna Samanta International Journal of Molecular Sciences 2019 Volume 20, Issue 2 "... Based on the concentration of round cells and leukocytes, and the sample processing, the experimental groups were defined as follows: Group 1 contained neat semen with round cells and leukocytes ≥ 1 × 10^6/mL; group 2 contained neat...

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Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound

Posted by Leanne Kodsmann on

Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound

Mouse CD1 Plasma, Rat Plasma, and Pooled Human Plasma from Innovative Research were used in the following study:   Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound Lara Pes, Stephan David Koester, Johannes Pall Magnusson, Serghei Chercheja, Federico Medda, Khalid Abu Ajaj, Didier Rognan, Steffen Daum, Friederike Inga Nollmann, Javier Garcia Fernandez, Patricia Perez Galan, Heidi-Kristin Walter, Anna Warnecke, Felix Kratz Journal of Controlled Release Volume 296, 28 February 2019, Pages 81-92 "... AE-KetoSulf07 and AE-Ester-Sulf07 are novel acid-sensitive albumin-binding prodrugs demonstrating tumor regressions in all of the evaluated human tumor xenograft...

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A proteome-wide screen of Campylobacter jejuni using protein microarrays identifies novel and conformational antigens

Posted by Leanne Kodsmann on

A proteome-wide screen of Campylobacter jejuni using protein microarrays identifies novel and conformational antigens

Pooled Human Serum from Innovative Research was used in the following study:   A proteome-wide screen of Campylobacter jejuni using protein microarrays identifies novel and conformational antigens Jiayou Liu, Jodi R. Parrish, Julie Hines, Linda Mansfield, Russell L. Finley Jr. PLOS | ONE Published: January 11, 2019 "... Mouse antiserum was from mice orally challenged with C. jejuni strain NCTC11168 (24 days post infection) as described [45]. Pooled human sera from 10 healthy individuals (cat. no. IPLA-SER) was obtained from Innovative Research (Novi, MI). Purified GST [46] was used as standard ..."   Related products available from Innovative Research also...

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Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry

Posted by Leanne Kodsmann on

Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry

Single Donor Human Plasma from Innovative Research was used in the following study:   Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry Xun Bao, Jianmei Wu, Nader Sanai, Jing Li Journal of Pharmaceutical and Biomedical Analysis Volume 166, 20 March 2019, Pages 197-204 "... Drug-free (blank) human plasma from six different healthy donors and pooled plasma (with Na-EDTA anticoagulant) were purchased from Innovative Research Inc. (Novi, MI, USA) ... Frozen plasma and tumor samples were thawed at room temperature. Patient plasma samples were diluted 5-fold with blank...

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HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study

Posted by Leanne Kodsmann on

HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study

Human Plasma from Innovative Research was used in the following study:   HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study Derek E. Murrell, David B. Cluck, Jonathan P. Moorman, Stacy D. Brown, Ke-Sheng Wang, Michelle M. Duffourc, Sam Harirforoosh Clinical Drug Investigation March 2019, Volume 39, Issue 3, pp 285–299 "... Plasma, for pharmacokinetic analysis, and remaining cells, for genetic testing, were separated then placed at −80 °C until analysis. Samples were analyzed using a previously validated liquid chromatography-mass spectrometry (LC–MS) assay developed by Simiele et al., with modifcations [25]. Briefy, a standard curve ranging from 10 ng/ml to 1500 ng/ml...

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