Product References

The Binding Mechanisms of Antibodies to DNA from Healthy Subjects and Patients with Systemic Lupus Erythematosus: The Role of Monogamous Bivalency and Fc Dependence

Posted by Adam Awdish on

The Binding Mechanisms of Antibodies to DNA from Healthy Subjects and Patients with Systemic Lupus Erythematosus: The Role of Monogamous Bivalency and Fc Dependence

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   The Binding Mechanisms of Antibodies to DNA from Healthy Subjects and Patients with Systemic Lupus Erythematosus: The Role of Monogamous Bivalency and Fc Dependence Morgan E. Belina, Diane M. Spencer, and David S. Pisetsky ImmunoHorizons February 1, 2022 Antibodies that target DNA (anti-DNA) are a unique subset of antibodies which bind to the structural components of DNA molecules. They were originally observed within the context of systemic lupus erythematosus (SLE), and anti-DNA in SLE appeared to have the ability to bind DNA regardless of...

Read more →

Anesthetic Pharmacology of the Mint Extracts L-Carvone and Methyl Salicylate

Posted by Adam Awdish on

Anesthetic Pharmacology of the Mint Extracts L-Carvone and Methyl Salicylate

Innovative Grade US Origin Rat Sprague Dawley Serum from Innovative Research was used in the following study:   Anesthetic Pharmacology of the Mint Extracts L-Carvone and Methyl Salicylate Robert J. Brosnan, Kimberly Ramos, Antonio Jose de Araujo Aguiar, Alessia Cenani, Heather K. Knych Pharmacology January 31, 2022 Many anesthetics in use today work via interactions with a select group of ion channel targets. Specifically, most anesthetics target γ-amino butyric acid type A (GABAA) and N-methyl-D-aspartate (NMDA) receptors, as well as type-2 voltage-gated sodium (Nav1.2) channels. While injectable anesthetics typically have a high affinity for one specific ion channel, inhaled anesthetics, on...

Read more →

LC-MS/MS Method for Simultaneous Quantification of the First-Line Anti-Tuberculosis Drugs and Six Primary Metabolites in Patient Plasma: Implications for Therapeutic Drug Monitoring

Posted by Adam Awdish on

LC-MS/MS Method for Simultaneous Quantification of the First-Line Anti-Tuberculosis Drugs and Six Primary Metabolites in Patient Plasma: Implications for Therapeutic Drug Monitoring

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   LC-MS/MS Method for Simultaneous Quantification of the First-Line Anti-Tuberculosis Drugs and Six Primary Metabolites in Patient Plasma: Implications for Therapeutic Drug Monitoring Agnija Kivrane, Solveiga Grinberga, Eduards Sevostjanovs, Viktorija Igumnova, Ilva Pole, Anda Viksna, Dace Bandere, Alvils Krams, Andra Cirule, Osvalds Pugovics, Renate Ranka Journal of Chromatography B November 15, 2021 Tuberculosis (TB) is an infection caused by an airborne bacteria called Mycobacterium tuberculosis. Despite the advances in treating TB over the years there is still an estimated 10 million new cases around the...

Read more →

Sugar Shock: Probing Streptococcus Pyogenes Metabolism Through Bioluminescence Imaging

Posted by Adam Awdish on

Sugar Shock: Probing Streptococcus Pyogenes Metabolism Through Bioluminescence Imaging

Innovative Grade US Origin Mouse C57BL6 Plasma from Innovative Research was used in the following study:   Sugar Shock: Probing Streptococcus Pyogenes Metabolism Through Bioluminescence Imaging Richard W. Davis IV, Charlotte G. Muse, Heather Eggleston, Micaila Hill, Peter Panizzi bioRxiv January 16, 2022 Despite having limited use in diagnostic medical settings, light-producing bacterium can be extremely useful in pre-clinical experiments by giving the opportunity to track in real-time the spread of these pathogens throughout the course of an infection. A major limitation to using these pathogens in research, however, is the gap in understanding the changes in light production observed...

Read more →

Factor VII Activating Protease (FSAP) Inhibits the Outcome of Ischemic Stroke in Mouse Models

Posted by Adam Awdish on

Factor VII Activating Protease (FSAP) Inhibits the Outcome of Ischemic Stroke in Mouse Models

Mouse Total Fibrinogen ELISA Kit from Innovative Research was used in the following study:   Factor VII Activating Protease (FSAP) Inhibits the Outcome of Ischemic Stroke in Mouse Models Jeong Yeon Kim, Dipankar Manna, Trygve B. Leergaard, Sandip M. Kanse bioRxiv January 12, 2022 Factor VII activating protease (FSAP) is a serine protease associated with cell adhesion, and patients diagnosed with the Marburg I (MI) single nucleotide polymorphism (SNP) have an increased chance of stroke due to inactivation of the FSAP enzyme. Observations in both human patients that have suffered a stroke and in vitro mouse models have shown raised plasma FSAP...

Read more →


×