Product References

Cytoprotective IgG Antibodies in Sera from a Subset of Patients with AQP4‑IgG Seropositive Neuromyelitis Optica Spectrum Disorder

Posted by Adam Awdish on

Cytoprotective IgG Antibodies in Sera from a Subset of Patients with AQP4‑IgG Seropositive Neuromyelitis Optica Spectrum Disorder

Single Donor Human Complement Serum from Innovative Research was used in the following study:   Cytoprotective IgG Antibodies in Sera from a Subset of Patients with AQP4‑IgG Seropositive Neuromyelitis Optica Spectrum Disorder LukmaneeTradtrantip, Michael R. Yeaman & A. S. Verkman Scientific Reports November 9, 2021 Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disorder that attacks the central nervous system and can cause demyelination in the optic nerve, spinal cord, and brain, and potentially cause further neurological deficits. Over 70% of patients suffering from NMOSD are seropositive for IgG autoantibodies which target extracellular epitopes of astrocyte water channel aquaporin-4 (AQP4),...

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Reagent Filming for Universal Point-of-Care Diagnostics

Posted by Adam Awdish on

Reagent Filming for Universal Point-of-Care Diagnostics

Pooled Human Urine from Innovative Research was used in the following study:   Reagent Filming for Universal Point-of-Care Diagnostics Gyeo-Re Han, Hyungjun Jang, Hangil Ki, Hoyeon Lee, and Min-Gon Kim Small Methods 2021 Global medical centers, especially places like outdoor clinics and community health centers, benefit from simplified and decentralized point-of-care testing (POCT) due to their affordability, accessibility, and ease of operation. These factors allow for disease diagnosis in resource-limited settings or in uncontrolled environments, such as field clinics in catastrophe or poverty-affected regions. Simplifying assays, however, comes with its own set of challenges to overcome. For example, translating more...

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Integrated Dielectrophoretic and Impedimetric Biosensor Provides a Template for Universal Biomarker Sensing in Clinical Samples

Posted by Adam Awdish on

Integrated Dielectrophoretic and Impedimetric Biosensor Provides a Template for Universal Biomarker Sensing in Clinical Samples

Single Donor Human Serum Off The Clot from Innovative Research was used in the following study:   Integrated Dielectrophoretic and Impedimetric Biosensor Provides a Template for Universal Biomarker Sensing in Clinical Samples Logeeshan Velmanickam, Vidura Jayasooriya, Dharmakeerthi Nawarathna Electrophoresis January 20, 2021 The use of circulating biomarker tests is common in the screening and diagnosis of various diseases and infections. These tests commonly target biomarkers such as DNA, miRNA, and proteins, however, these different molecules all require different testing procedures and assays which increase the time and costs associated with diagnosis. Miniaturized testing devices have been utilized as a faster...

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Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease

Posted by Adam Awdish on

Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease

Human PAI-1 ELISA Kit from Innovative Research (Molecular Innovations) was used in the following study:   Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease Peter Simons, Yan Guo, Virginie Bondu, Susan L. Tigert, Michelle Harkins, Samuel Goodfellow, Cana Tompkins, Devon Chabot-Richards, Xuexian O. Yang, Laura Gonzalez Bosc, Steven Bradfute, Daniel A. Lawrence, and Tione Buranda Viruses August 12, 2021 Hantavirus cardiopulmonary syndrome (HCPS) cases are characterized by loss of pulmonary vascular endothelial integrity that has the potential to cause acute pulmonary edema. HCPS tends to present high levels of...

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Identification of the Factor XII Contact Activation Site Enables Sensitive Coagulation Diagnostics

Posted by Adam Awdish on

Identification of the Factor XII Contact Activation Site Enables Sensitive Coagulation Diagnostics

Human Factor XII Purified, Human Kallikrein Purified, and Human Prekallikrein Purified from Molecular Innovations were used in the following study:   Identification of the Factor XII Contact Activation Site Enables Sensitive Coagulation Diagnostics Marco Heestermans, Clément Naudin, Reiner K. Mailer, Sandra Konrath, Kristin Klaetschke, Anne Jämsä, Maike Frye, Carsten Deppermann, Giordano Pula, Piotr Kuta, Manuel A. Friese, Mathias Gelderblom, Albert Sickmann, Roger J. S. Preston, Jerzy-Roch Nofer, Stefan Rose-John, Lynn M. Butler, Ophira Salomon, Evi X. Stavrou, and Thomas Renné Nature Communications September 22, 2021 Blood coagulation is an essential part of stopping bleeding at the site of vascular injuries....

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