Product References — Pooled Human Plasma Apheresis Derived

Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system

Posted by Corey Marcath on

Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system Ali Hariri, Eric Zhao, Ananthakrishna Soundaram Jeevarathinam, Jeanne Lemaster, Jianjian Zhang & Jesse V. Jokerst Scientific Reports 06 August 2019 “…LED-based photoacoustic imaging has practical value in that it is affordable and rugged; however, this technology has largely been confined to anatomic imaging with limited applications into functional or molecular imaging. Here, we report molecular imaging reactive oxygen and nitrogen species (RONS) with a near-infrared (NIR) absorbing small molecule (CyBA) and LED-based photoacoustic imaging...

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Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS

Posted by Corey Marcath on

Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS Christofer A. Q. Karlsson, Sofia Jarnum, Lena Winstedt, Christian Kjellman, Lars Bjorck, Adam Linder‡, Johan A. Malmstro The American Society for Biochemistry and Molecular Biology March 6, 2018 ”…The molecular interplay between host and pathogen is complex and under considerable evolutionary pressure. Determining the structure, function and dynamics of all host pathogen interactions in a systems-wide and quantitative manner is a formidable and fundamental challenge in medical microbiology....

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Synthesis of gold nanocluster-loaded lysozyme nanoparticles for label-free ratiometric fluorescent pH sensing: applications to enzyme–substrate systems and cellular imaging

Posted by Corey Marcath on

Synthesis of gold nanocluster-loaded lysozyme nanoparticles for label-free ratiometric fluorescent pH sensing: applications to enzyme–substrate systems and cellular imaging

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Synthesis of gold nanocluster-loaded lysozyme nanoparticles for label-free ratiometric fluorescent pH sensing: applications to enzyme–substrate systems and cellular imaging Shanmugam Chandirasekar,a Jyun-Guo You,a Jhe-Hong Xuea, Wei-Lung Tseng Journal of Materials Chemistry B 17 May 2019 “…Intracellular pH is one of the most indispensable factors for the function and metabolism processes of a cell, such as cell membrane polarity, cellular signaling, vesicle trafficking, cell volume regulation, cell proliferation and apoptosis.. …For the determination of the urea level in real-world samples, pooled normal human plasma was purchased...

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Quantification of U-47700 and its metabolites in plasma by LC-MS/MS

Posted by Leanne Kodsmann on

Quantification of U-47700 and its metabolites in plasma by LC-MS/MS

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Quantification of U-47700 and its metabolites in plasma by LC-MS/MS Christina R. Smith, Michael T. Truver, Madeleine J. Swortwood Journal of Chromatography B Volume 1112, 1 April 2019, Pages 41-47 "... Novel Synthetic Opioids (NSO) have caused a recent epidemic both nationally and globally. NSO have gained popularity in the illicit drug market and have brought about an increase in fentanyl and its derivatives, as well as other chemically unrelated opioid agonists. U-47700, a non-fentanyl analog analgesic opioid, was first developed by The Upjohn Company...

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Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound

Posted by Leanne Kodsmann on

Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound

Mouse CD1 Plasma, Rat Plasma, and Pooled Human Plasma from Innovative Research were used in the following study:   Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound Lara Pes, Stephan David Koester, Johannes Pall Magnusson, Serghei Chercheja, Federico Medda, Khalid Abu Ajaj, Didier Rognan, Steffen Daum, Friederike Inga Nollmann, Javier Garcia Fernandez, Patricia Perez Galan, Heidi-Kristin Walter, Anna Warnecke, Felix Kratz Journal of Controlled Release Volume 296, 28 February 2019, Pages 81-92 "... AE-KetoSulf07 and AE-Ester-Sulf07 are novel acid-sensitive albumin-binding prodrugs demonstrating tumor regressions in all of the evaluated human tumor xenograft...

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