Product References — Pooled Human Plasma Apheresis Derived

Photooxidation-Induced Fluorescence Amplification System for an Ultra-Sensitive Enzyme-Linked Immunosorbent Assay (ELISA)

Posted by Adam Awdish on

Photooxidation-Induced Fluorescence Amplification System for an Ultra-Sensitive Enzyme-Linked Immunosorbent Assay (ELISA)

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Photooxidation-Induced Fluorescence Amplification System for an Ultra-Sensitive Enzyme-Linked Immunosorbent Assay (ELISA) Youhee Heo, Kwanwoo Shin, Min Cheol Park, and Ji Yoon Kang Scientific Reports March 12, 2021 It’s important to be able to detect biomarkers, such as proteins or nucleic acids, at very low concentrations in various bodily fluids when attempting to diagnose diseases. There has been a lot of contemporary research looking to identify other disease biomarkers, particularly ones detectable in blood, and reliable methods for detecting said biomarkers with low cost and high...

Read more →

Nucleic Acid Sample Preparation Using Magnetic Ionic Liquids as Cell Lysis and DNA Extraction Solvents

Posted by Adam Awdish on

Nucleic Acid Sample Preparation Using Magnetic Ionic Liquids as Cell Lysis and DNA Extraction Solvents

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Nucleic acid Sample Preparation Using Magnetic Ionic Liquids as Cell Lysis and DNA Extraction Solvents Miranda N. Emaus Iowa State University Graduate Theses and Dissertations 2021 When preparing DNA samples from cells with disrupted membranes, the first step on sample preparation is generally cell lysis. DNA is then extracted after cell lysis and then analysis of the nucleic acid is performed. However, current sample preparation methods are time consuming, multi-step processes. Magnetic ionic liquids (MILs) are salts in a molten form which are susceptible to...

Read more →

A Systematic Study of the In Vitro Pharmacokinetics and Estimated Human In Vivo Clearance of Indole and Indazole-3-Carboxamide Synthetic Cannabinoid Receptor Agonists Detected on the Illicit Drug Market

Posted by Adam Awdish on

A Systematic Study of the In Vitro Pharmacokinetics and Estimated Human In Vivo Clearance of Indole and Indazole-3-Carboxamide Synthetic Cannabinoid Receptor Agonists Detected on the Illicit Drug Market

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   A Systematic Study of the In Vitro Pharmacokinetics and Estimated Human In Vivo Clearance of Indole and Indazole-3-Carboxamide Synthetic Cannabinoid Receptor Agonists Detected on the Illicit Drug Market Andrew M. Brandon, Lysbeth H. Antonides, Jennifer Riley, Ola Epemolu, Denise A. McKeown, Kevin D. Read, and Craig McKenzie Molecules March 5, 2021 A new, diverse group of synthetic drugs designed to activate human cannabinoid receptors CB1 and CB2 have emerged in the illicit drug market over recent years. These synthetic cannabinoid receptor agonists (SCRAs) have been...

Read more →

Can Remdesivir and its Parent Nucleoside GS-441524 be Potential Oral Drugs? An in vitro and in vivo DMPK Assessment

Posted by Adam Awdish on

Can Remdesivir and its Parent Nucleoside GS-441524 be Potential Oral Drugs? An in vitro and in vivo DMPK Assessment

Innovative Grade US Origin Mouse CD1 Plasma and Pooled Human Plasma Apheresis Derived from Innovative Research were used in the following study:   Can Remdesivir and its Parent Nucleoside GS-441524 be Potential Oral Drugs? An in vitro and in vivo DMPK Assessment Jiashu Xie, Zhengqiang Wang Acta Pharmaceutica Sinica B March 5, 2021 To date, the only FDA-approved drug for treating COVID-19 is Remdesivir (RDV), which can only be administered intravenously. RDV is a ProTide drug derived from nucleoside GS-441524, and the potency of RDV is dependent on intracellular conversion into GS-441524 triphosphate. In vitro studies of RDV in human...

Read more →

Metabolism of a Kratom Alkaloid Metabolite in Human Plasma Increases Its Opioid Potency and Efficacy

Posted by Adam Awdish on

Metabolism of a Kratom Alkaloid Metabolite in Human Plasma Increases Its Opioid Potency and Efficacy

Mouse Non-Swiss Albino Plasma and Pooled Human Plasma Apheresis Derived from Innovative Research were used in the following study:   Metabolism of a Kratom Alkaloid Metabolite in Human Plasma Increases Its Opioid Potency and Efficacy Shyam H. Kamble, Francisco León, Tamara I. King, Erin C. Berthold, Carolina Lopera-Londoño, Kanumuri Siva Rama Raju, Aidan J. Hampson, Abhisheak Sharma, Bonnie A. Avery, Lance R. McMahon, and Christopher R. McCurdy ACS Pharmacology & Translational Science July 31, 2020 Kratom is commonly used in the United States for self-treatment of pain and opioid withdrawal symptoms. Mitragynine is the most abundant alkaloid in kratom, and...

Read more →


×