Product References — Pooled Human Plasma Apheresis Derived

LC-MS/MS analysis of plasma glucosylsphingosine as a biomarker for diagnosis and follow-up monitoring in Gaucher disease in the Spanish population

Posted by Corey Marcath on

LC-MS/MS analysis of plasma glucosylsphingosine as a biomarker for diagnosis and follow-up monitoring in Gaucher disease in the Spanish population

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   LC-MS/MS analysis of plasma glucosylsphingosine as a biomarker for diagnosis and follow-up monitoring in Gaucher disease in the Spanish population Pilar Irún, Jorge J. Cebolla, Laura López de Frutos, Isabel De Castro-Orós, Mercedes Roca-Espiau and Pilar Giraldo Clinical Chemistry and Laboratory Medicine (CCLM) February 3, 2020 The method was validated according to the guidelines of the US Food and Drug administration [33]. Briefly, matrix effects were assessed by analyzing five repetitions of a mixture of IS and ES in methanol and also spiking the same...

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Development of a Linker Mediated Immunoassay Using Chemically Transitioned Nanosensors

Posted by Corey Marcath on

Development of a Linker Mediated Immunoassay Using Chemically Transitioned Nanosensors

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Development of a Linker Mediated Immunoassay Using Chemically Transitioned Nanosensors Lucas D Smith, Michael Charles Willard, Jordan P. Smith, and Brian T. Cunningham Analytical Chemistry 2/8/2020 “Sensitive and specific quantification of protein biomarkers is important in medical diagnostics, academic research, and pharmaceutical development. However, multiple binding steps in conventional sandwich immunoassay protocols result in high assay hands-on-time and delayed results. This is particularly relevant for medical diagnostics, where assay turn-around-time can have an immense impact on patient outcomes. …CTNI samples were prepared using PBS or...

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Measurement of Thrombolysis Enhanced by EkoSonic Catheter-Based Endovascular Therapy

Posted by Corey Marcath on

Measurement of Thrombolysis Enhanced by EkoSonic Catheter-Based Endovascular Therapy

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Measurement of Thrombolysis Enhanced by EkoSonic Catheter-Based Endovascular Therapy Alexander Hannah, Misty L. Noble-Vranish, Curtis Genstler IEEE International Ultrasonics Symposium 6-9 Oct. 2019 “…Ultrasound (US) imaging is a valuable tool to visualize and measure the underlying anatomy and physiology indicative of vascular pathology. Imaging can identify the location and severity of thrombosis, and it can monitor interventions. It has been widely used for guidance in HIFU-based therapies… Pooled normal human plasma was obtained from Innovative Research (Novi, MI)…”   Related products available from Innovative Research...

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Solid-Phase Microextraction Enables Isolation of BRAF V600E Circulating Tumor DNA from Human Plasma for Detection with a Molecular Beacon Loop-Mediated Isothermal Amplification Assay

Posted by Corey Marcath on

Solid-Phase Microextraction Enables Isolation of BRAF V600E Circulating Tumor DNA from Human Plasma for Detection with a Molecular Beacon Loop-Mediated Isothermal Amplification Assay

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Solid-Phase Microextraction Enables Isolation of BRAF V600E Circulating Tumor DNA from Human Plasma for Detection with a Molecular Beacon Loop-Mediated Isothermal Amplification Assay Marcelino Varona, Derek R. Eitzmann, Darshna Pagariya, Robbyn K. Anand, and Jared L. Anderson Analytical Chemistry 17 Jan 2020 ”Circulating tumor DNA (ctDNA) is a promising biomarker that can provide a wealth of information regarding the genetic makeup of cancer as well as provide a guide for monitoring treatment. Methods for rapid and accurate profiling of ctDNA are highly desirable in order...

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Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system

Posted by Corey Marcath on

Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:   Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system Ali Hariri, Eric Zhao, Ananthakrishna Soundaram Jeevarathinam, Jeanne Lemaster, Jianjian Zhang & Jesse V. Jokerst Scientific Reports 06 August 2019 “…LED-based photoacoustic imaging has practical value in that it is affordable and rugged; however, this technology has largely been confined to anatomic imaging with limited applications into functional or molecular imaging. Here, we report molecular imaging reactive oxygen and nitrogen species (RONS) with a near-infrared (NIR) absorbing small molecule (CyBA) and LED-based photoacoustic imaging...

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