Product References — Pooled Human Plasma Apheresis Derived

Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform

Posted by Leanne Kodsmann on

Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform

Human Whole Blood, Pooled Human Serum, and Pooled Human Plasma from Innovative Research were used in the following study:   Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform Christopher R. Phaneuf, Kyle J. Seamon, Tyler P. Eckles, Anchal Sinha, Joseph S. Schoeniger, Brooke Harmon, Robert J. Meagher, Vinay V. Abhyankar and Chung-Yan Koh Analytical Methods Issue 5, 2019 "... The potential for accidental exposure, malicious use, or undesirable persistence of Cas9 therapeutics and off-target genome effects highlight the need for detection assays. Here we report a centrifugal microfluidic platform for the measurement of both Cas9 protein levels and nuclease...

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Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases

Posted by Leanne Kodsmann on

Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases

Human Plasma from Innovative Research was used in the following study:   Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases Takuma Ohmichi, Masato Mitsuhashi, Harutsugu Tatebe, Takashi Kasai, Omar M. Ali El-Agnaf, Takahiko Tokuda Parkinsonism & Related Disorders Volume 61, April 2019, Pages 82-87 "... In brief, forty μL each of standards, controls, and plasma samples were applied to each well of ELISA plates with immobilized monoclonal antibodies against SNAP25, EAAT1, or OMG, and incubated overnight. ... Since our sandwich ELISA used a combination of 2 different target antibodies, such as anti-CD81...

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Development of a mass spectrometry based detection method for the mitochondrion‐derived peptide MOTS‐c in plasma samples for doping control purposes

Posted by Leanne Kodsmann on

Development of a mass spectrometry based detection method for the mitochondrion‐derived peptide MOTS‐c in plasma samples for doping control purposes

Human Plasma and Human AB Serum from Innovative Research were used in the following study:   Development of a mass spectrometry based detection method for the mitochondrion‐derived peptide MOTS‐c in plasma samples for doping control purposes Andre Knoop, Andreas Thomas, Mario Thevis Rapid Communications in Mass Spectrometry November 2018 "... In the field of anti-doping research, the development and improvement of detection methods concerning new substances that potentially exhibit performance-enhancing properties is of utmost importance ... For method development and validation, commercially available pooled human plasma (male AB plasma in K2EDTA) and human serum TYPE AB (male) from Innovative Research,...

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A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against Staphylococcus aureus Small-Colony Variants

Posted by Leanne Kodsmann on

A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against Staphylococcus aureus Small-Colony Variants

Pooled Human Plasma from Innovative Research was used in the following study:   A High-Throughput Screening Approach To Repurpose FDA-Approved Drugs for Bactericidal Applications against Staphylococcus aureus Small-Colony Variants Ryan P. Trombetta, Paul M. Dunman, Edward M. Schwarz, Stephen L. Kates, Hani A. Awad American Society for Microbiology October 2018, mSphere open-acces article "... Briefly, overnight cultures of UAMS-1 were adjusted to ∼1 × 10^6 CFU/ml in TSB supplemented with 10% (vol/vol) pooled human plasma (Innovative Research, Novi, MI) and added to individual wells of MBEC plates at a volume of 150 µl. Plates were incubated for 24 h at 37°C with shaking...

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Development and validation of LC-MS/MS method for quantification of bictegravir in human plasma and its application to an intracellular uptake study

Posted by Leanne Kodsman on

Human Plasma with K2 EDTA from Innovative Research was recently used in the following study: Development and validation of LC-MS/MS method for quantification of bictegravir in human plasma and its application to an intracellular uptake study Pavan Kumar Prathipati, Subhra Mandal, Christopher J. Destache Biomedical Chromatography, September 2018 " ... A sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for quantification of bictegravir in human plasma... Dipotassium ethylenediaminetetraacetic acid (K2EDTA) plasma was purchased from Innovative Research (Novi, MI)... Six different sources of K2EDTA human blank plasma were extracted and the peak areas at the retention time of...

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