Product References — Pooled Human Plasma Apheresis Derived

Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry

Posted by Leanne Kodsmann on

Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry

Single Donor Human Plasma from Innovative Research was used in the following study:   Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry Xun Bao, Jianmei Wu, Nader Sanai, Jing Li Journal of Pharmaceutical and Biomedical Analysis Volume 166, 20 March 2019, Pages 197-204 "... Drug-free (blank) human plasma from six different healthy donors and pooled plasma (with Na-EDTA anticoagulant) were purchased from Innovative Research Inc. (Novi, MI, USA) ... Frozen plasma and tumor samples were thawed at room temperature. Patient plasma samples were diluted 5-fold with blank...

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HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study

Posted by Leanne Kodsmann on

HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study

Human Plasma from Innovative Research was used in the following study:   HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study Derek E. Murrell, David B. Cluck, Jonathan P. Moorman, Stacy D. Brown, Ke-Sheng Wang, Michelle M. Duffourc, Sam Harirforoosh Clinical Drug Investigation March 2019, Volume 39, Issue 3, pp 285–299 "... Plasma, for pharmacokinetic analysis, and remaining cells, for genetic testing, were separated then placed at −80 °C until analysis. Samples were analyzed using a previously validated liquid chromatography-mass spectrometry (LC–MS) assay developed by Simiele et al., with modifcations [25]. Briefy, a standard curve ranging from 10 ng/ml to 1500 ng/ml...

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Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform

Posted by Leanne Kodsmann on

Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform

Human Whole Blood, Pooled Human Serum, and Pooled Human Plasma from Innovative Research were used in the following study:   Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform Christopher R. Phaneuf, Kyle J. Seamon, Tyler P. Eckles, Anchal Sinha, Joseph S. Schoeniger, Brooke Harmon, Robert J. Meagher, Vinay V. Abhyankar and Chung-Yan Koh Analytical Methods Issue 5, 2019 "... The potential for accidental exposure, malicious use, or undesirable persistence of Cas9 therapeutics and off-target genome effects highlight the need for detection assays. Here we report a centrifugal microfluidic platform for the measurement of both Cas9 protein levels and nuclease...

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Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases

Posted by Leanne Kodsmann on

Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases

Human Plasma from Innovative Research was used in the following study:   Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases Takuma Ohmichi, Masato Mitsuhashi, Harutsugu Tatebe, Takashi Kasai, Omar M. Ali El-Agnaf, Takahiko Tokuda Parkinsonism & Related Disorders Volume 61, April 2019, Pages 82-87 "... In brief, forty μL each of standards, controls, and plasma samples were applied to each well of ELISA plates with immobilized monoclonal antibodies against SNAP25, EAAT1, or OMG, and incubated overnight. ... Since our sandwich ELISA used a combination of 2 different target antibodies, such as anti-CD81...

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Development of a mass spectrometry based detection method for the mitochondrion‐derived peptide MOTS‐c in plasma samples for doping control purposes

Posted by Leanne Kodsmann on

Development of a mass spectrometry based detection method for the mitochondrion‐derived peptide MOTS‐c in plasma samples for doping control purposes

Human Plasma and Human AB Serum from Innovative Research were used in the following study:   Development of a mass spectrometry based detection method for the mitochondrion‐derived peptide MOTS‐c in plasma samples for doping control purposes Andre Knoop, Andreas Thomas, Mario Thevis Rapid Communications in Mass Spectrometry November 2018 "... In the field of anti-doping research, the development and improvement of detection methods concerning new substances that potentially exhibit performance-enhancing properties is of utmost importance ... For method development and validation, commercially available pooled human plasma (male AB plasma in K2EDTA) and human serum TYPE AB (male) from Innovative Research,...

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