Product References — Animal Blood Cells

Effects of Inflammation and Soluble Epoxide Hydrolase Inhibition on Oxylipin Composition of Very Low‐Density Lipoproteins in Isolated Perfused Rat Livers

Posted by Adam Awdish on

Effects of Inflammation and Soluble Epoxide Hydrolase Inhibition on Oxylipin Composition of Very Low‐Density Lipoproteins in Isolated Perfused Rat Livers

Sheep Red Blood Cells Packed 100% from Innovative Research was used in the following study:   Effects of Inflammation and Soluble Epoxide Hydrolase Inhibition on Oxylipin Composition of Very Low‐Density Lipoproteins in Isolated Perfused Rat Livers Rachel E. Walker, Olga V. Savinova, Theresa L. Pedersen, John W. Newman, Gregory C. Shearer Physiological Reports February 24, 2021 Oxylipins are metabolized from polyunsaturated fatty acids (PUFA) by enzymes of the lipoxygenase (LOX) and cytochrome P450 (CYP450) families and mediate cardiovascular health via modifying inflammation, thrombosis, hemostasis, and vascular tone. Although the oxylipin metabolites of arachidonic acid (AA) have been extensively studied, there...

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The Selenoprotein MsrB1 Instructs Dendritic Cells to Induce T-Helper 1 Immune Responses

Posted by Adam Awdish on

The Selenoprotein MsrB1 Instructs Dendritic Cells to Induce T-Helper 1 Immune Responses

Sheep Red Blood Cells Packed 100% from Innovative Research was used in the following study:   The Selenoprotein MsrB1 Instructs Dendritic Cells to Induce T-Helper 1 Immune Responses Ho-Jae Lee, Joon Seok Park, Hyun Jung Yoo, Hae Min Lee, Byung Cheon Lee, and Ji Hyung Kim Antioxidants October 20, 2020 Reduction–oxidation (Redox) reactions are important biological reactions that participate in diverse physiological processes throughout the body. One particular Redox reaction is protein oxidation, which is performed by reactive oxygen species (ROS), and is of vital importance in regulating cellular signal transduction, metabolism, and protein activity. There are a select few sulfur-containing...

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Sensitive and Rapid UHPLC–MS/MS Assay for Simultaneous Quantifications of Calcipotriol and Paclitaxel in Rat Whole Blood and Plasma Samples

Posted by Adam Awdish on

Sensitive and Rapid UHPLC–MS/MS Assay for Simultaneous Quantifications of Calcipotriol and Paclitaxel in Rat Whole Blood and Plasma Samples

Innovative Grade US Origin Rat Sprague Dawley Whole Blood and Innovative Grade US Origin Rat Sprague Dawley Plasma from Innovative Research was used in the following study:   Sensitive and Rapid UHPLC–MS/MS Assay for Simultaneous Quantifications of Calcipotriol and Paclitaxel in Rat Whole Blood and Plasma Samples Victor R. Lincha, Cheng-Hui Hsiao, Jun Zhao, Chun Li, Diana S-L Chow Journal of Pharmaceutical and Biomedical Analysis October 9, 2020 The potential benefits of stroma-depleting agents combined with chemotherapy for pancreatic ductal adenocarcinoma (PDAC) treatment has been examined in vitro and in transplantation studies. Unfortunately, this type of treatment has failed in...

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Biomimetic Anisotropic Polymeric Nanoparticles Coated with Red Blood Cell Membranes for Enhanced Circulation and Toxin Removal

Posted by Adam Awdish on

Biomimetic Anisotropic Polymeric Nanoparticles Coated with Red Blood Cell Membranes for Enhanced Circulation and Toxin Removal

Innovative Grade US Origin Mouse CD1 Whole Blood from Innovative Research was used in the following study:   Biomimetic Anisotropic Polymeric Nanoparticles Coated with Red Blood Cell Membranes for Enhanced Circulation and Toxin Removal Elana Ben-Akiva, Randall A. Meyer, Hongzhe Yu, Jonathan T. Smith, Drew M. Pardoll, Jordan J. Green Science Advances April 15, 2020 Therapeutic devices based on biomaterials can have enhanced function due to mimicry of naturally occurring structures. Cell membrane coatings can be used to mimic the functionality of various cell types, enhancing delivery properties, and extending the half-life of blood circulation. However, previous studies have used...

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Supramolecular Assembly of Toll-like Receptor 7/8 Agonist into Multimeric Water-Soluble Constructs Enables Superior Immune Stimulation In Vitro and In Vivo

Posted by Adam Awdish on

Supramolecular Assembly of Toll-like Receptor 7/8 Agonist into Multimeric Water-Soluble Constructs Enables Superior Immune Stimulation In Vitro and In Vivo

Porcine Red Blood Cells Packed 10% from Innovative Research was used in the following study:   Supramolecular Assembly of Toll-like Receptor 7/8 Agonist into Multimeric Water-Soluble Constructs Enables Superior Immune Stimulation In Vitro and In Vivo Alexander K. Andrianov, Alexander Marin, Ruixue Wang, Hatice Karauzum, Ananda Chowdhury, Pragati Agnihotri, Abdul S. Yunus, Roy A. Mariuzza, and Thomas R. Fuerst ACS Applied Bio Materials April 8, 2020 The magnitude to which a pathogen triggers an immune response depends largely on the activation of specific pattern recognition receptors (PRR), particularly Toll-like receptors (TLRs), expressed by cells at the infection site. TLR7/8 agonists...

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