Product References — Single Donor Human Red Blood Cells Washed

Reduction of Blood Volume Required to Perform Paper-Based Hematocrit Assays Guided by Device Design

Posted by Corey Marcath on

Reduction of Blood Volume Required to Perform Paper-Based Hematocrit Assays Guided by Device Design

Single Donor Human Red Blood Cells Washed from Innovative Research was used in the following study:   Reduction of Blood Volume Required to Perform Paper-Based Hematocrit Assays Guided by Device Design Syrena C. Fernandes, Keith R. Baillargeon, and Charles R. Mace Analytical Methods 22 Mar 2019 ”Point-of-care diagnostic tests can provide rapid and accurate information about the health of a patient without relying on the expensive equipment found in centralized laboratories. Not only does the development and application of these assays rely on the means of signal transduction, but also the method by which a sample is procured. …We obtained...

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Antibacterial isoamphipathic oligomers highlight the importance of multimeric lipid aggregation for antibacterial potency

Posted by Leanne Kodsmann on

Antibacterial isoamphipathic oligomers highlight the importance of multimeric lipid aggregation for antibacterial potency

Human Red Blood Cells from Innovative Research were used in the following study:   Antibacterial isoamphipathic oligomers highlight the importance of multimeric lipid aggregation for antibacterial potency Joseph S. Brown, Zeinab J. Mohamed, Christine M. Artim, Dana N. Thornlow, Joseph F. Hassler, Vincent P. Rigoglioso, Susan Daniel & Christopher A. Alabi Communications Biology volume 1, Article number: 220 (2018) "... This work has focused on the development of new experimental parameters for membrane-targeting antimicrobials, outside of the known properties of cationic charge and hydrophobicity. OligoTEAs have enabled the synthesis of isoamphipathic oligomers to specifically probe additional parameters in membrane disruption....

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Development of a Fast and Efficient Liposomal Drug Loading Technology for Poorly Water Soluble Drugs: Formulation, Characterization, and Potential Applications

Posted by Leanne Kodsman on

Development of a Fast and Efficient Liposomal Drug Loading Technology for Poorly Water Soluble Drugs: Formulation, Characterization, and Potential Applications

Human Red Blood Cells and Sheep Red Blood Cells from Innovative Research were used in the following study:   Development of a Fast and Efficient Liposomal Drug Loading Technology for Poorly Water Soluble Drugs: Formulation, Characterization, and Potential Applications Wei-Lun Tang The University of British Columbia (Vancouver), October 2018 "... Human and sheep red blood cells (RBCs) for hemolysis test were purchased from Innovative Research (Novi, MI) ... complete hemolysis of human and sheep RBCs was observed 1 h post incubation with free GA (40 µg GA /mL + 44 µg arginine/mL), whereas Lipo-GA (40 or 200 µg GA/mL) only...

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Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids

Posted by Leanne Kodsman on

Single Donor Human Red Blood Cells from Innovative Research were recently used in the following study: Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids Journal of Controlled Release Volume 286, 28 September 2018, Pages 46-54 Sam Chen, Josh Zaifman, Jayesh A. Kulkarni, Igor V. Zhigaltsev, Ying K. Tam, Marco A. Ciufolini, Yuen Yi C. Tam, Pieter R. Cullis "... The ability of LNP to cause hemolysis was assessed as follows. Briefly, human erythrocytes (RBC) (Innovative Research, Novi, MI) were washed three times with cold isotonic saline (0.9% w/v NaCl in water) and...

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Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery

Posted by Leanne Kodsman on

Human Red Blood Cells and Sheep Red Blood Cells from Innovative Research were recently used in the following study: Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery Wei-Lun Tang, Wei-Hsin Tang, Andras Szeitz, Jayesh Kulkarni, Pieter Cullis, Shyh-Dar Li Biomaterials, Volume 166, June 2018, Pages 13-26 ... Sepharose CL-4B, and Sephadex G-50 were purchased from Fisher Scientific (Ottawa, ON, Canada). Human and sheep red blood cells (RBCs) for hemolysis test were purchased from Innovative Research (Novi, MI). DiIC18 ...   Related products available from Innovative Research also include: Lyophilized Human...

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