Product References — Single Donor Human Plasma Whole Blood Derived

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   The Binding Mechanisms of Antibodies to DNA from Healthy Subjects and Patients with Systemic Lupus Erythematosus: The Role of Monogamous Bivalency and Fc Dependence Morgan E. Belina, Diane M. Spencer, and David S. Pisetsky ImmunoHorizons February 1, 2022 Antibodies that target DNA (anti-DNA) are a unique subset of antibodies which bind to the structural components of DNA molecules. They were originally observed within the context of systemic lupus erythematosus (SLE), and anti-DNA in SLE appeared to have the ability to bind DNA regardless of...

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   LC-MS/MS Method for Simultaneous Quantification of the First-Line Anti-Tuberculosis Drugs and Six Primary Metabolites in Patient Plasma: Implications for Therapeutic Drug Monitoring Agnija Kivrane, Solveiga Grinberga, Eduards Sevostjanovs, Viktorija Igumnova, Ilva Pole, Anda Viksna, Dace Bandere, Alvils Krams, Andra Cirule, Osvalds Pugovics, Renate Ranka Journal of Chromatography B November 15, 2021 Tuberculosis (TB) is an infection caused by an airborne bacteria called Mycobacterium tuberculosis. Despite the advances in treating TB over the years there is still an estimated 10 million new cases around the...

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Soluble Sema4D in Plasma of Head and Neck Squamous Cell Carcinoma Patients is Associated with Underlying Non-Inflamed Tumor Profile Rania H. Younis, Ioana Ghita, Manar Elnaggar, Risa Chaisuparat, Vasileios Ionas Theofilou, Donita Dyalram, Robert A. Ord, Eduardo Davila, Luke J. Tallon, John C. Papadimitriou, Tonya J. Webb, Søren M. Bentzen, and Joshua E. Lubek Frontiers in Immunology March 11, 2021 Semaphorin 4D (Sema4D) is a glycoprotein that is capable of functioning as both a membrane bound protein or as a cleaved soluble protein (sSema4D),...

Single Donor Human Whole Blood, Single Donor Human Plasma (Blood Derived), Single Donor Human Complement Serum, Innovative Grade US Origin Porcine Plasma, and Innovative Grade US Origin Porcine Whole Blood from Innovative Research were used in the following study:   Development of a Sensitive Assay to Screen Nanoparticles in vitro for Complement Activation Nuzhat Maisha, Tobias Coombs, and Erin B. Lavik American Chemical Society July 6, 2020 Nanomedicines are often recognized by the innate immune system as a threat, leading to unwanted clearance due to complement activation. This unwanted reaction not only alters the bioavailability of the therapeutic, but can...

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   An miRNA Fingerprint Using Neural-Enriched Extracellular Vesicles from Blood Plasma: Towards a Biomarker for Amyotrophic Lateral Sclerosis/Motor Neuron Disease Sandra Anne Banack, Rachael Anne Dunlop and Paul Alan Cox The Royal Society Publishing May 22, 2020 Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) continue to provide challenges for diagnosis since validated diagnostic biomarkers are currently unavailable. Rapid diagnosis and intervention in the disease process could be beneficial in slowing neurodegenerative disease progression as well...