Product References — Single Donor Human Plasma Whole Blood Derived

Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry

Posted by Leanne Kodsmann on

Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry

Single Donor Human Plasma from Innovative Research was used in the following study:   Determination of total and unbound ribociclib in human plasma and brain tumor tissues using liquid chromatography coupled with tandem mass spectrometry Xun Bao, Jianmei Wu, Nader Sanai, Jing Li Journal of Pharmaceutical and Biomedical Analysis Volume 166, 20 March 2019, Pages 197-204 "... Drug-free (blank) human plasma from six different healthy donors and pooled plasma (with Na-EDTA anticoagulant) were purchased from Innovative Research Inc. (Novi, MI, USA) ... Frozen plasma and tumor samples were thawed at room temperature. Patient plasma samples were diluted 5-fold with blank...

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HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study

Posted by Leanne Kodsmann on

HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study

Human Plasma from Innovative Research was used in the following study:   HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study Derek E. Murrell, David B. Cluck, Jonathan P. Moorman, Stacy D. Brown, Ke-Sheng Wang, Michelle M. Duffourc, Sam Harirforoosh Clinical Drug Investigation March 2019, Volume 39, Issue 3, pp 285–299 "... Plasma, for pharmacokinetic analysis, and remaining cells, for genetic testing, were separated then placed at −80 °C until analysis. Samples were analyzed using a previously validated liquid chromatography-mass spectrometry (LC–MS) assay developed by Simiele et al., with modifcations [25]. Briefy, a standard curve ranging from 10 ng/ml to 1500 ng/ml...

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Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases

Posted by Leanne Kodsmann on

Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases

Human Plasma from Innovative Research was used in the following study:   Quantification of brain-derived extracellular vesicles in plasma as a biomarker to diagnose Parkinson's and related diseases Takuma Ohmichi, Masato Mitsuhashi, Harutsugu Tatebe, Takashi Kasai, Omar M. Ali El-Agnaf, Takahiko Tokuda Parkinsonism & Related Disorders Volume 61, April 2019, Pages 82-87 "... In brief, forty μL each of standards, controls, and plasma samples were applied to each well of ELISA plates with immobilized monoclonal antibodies against SNAP25, EAAT1, or OMG, and incubated overnight. ... Since our sandwich ELISA used a combination of 2 different target antibodies, such as anti-CD81...

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Development of a mass spectrometry based detection method for the mitochondrion‐derived peptide MOTS‐c in plasma samples for doping control purposes

Posted by Leanne Kodsmann on

Development of a mass spectrometry based detection method for the mitochondrion‐derived peptide MOTS‐c in plasma samples for doping control purposes

Human Plasma and Human AB Serum from Innovative Research were used in the following study:   Development of a mass spectrometry based detection method for the mitochondrion‐derived peptide MOTS‐c in plasma samples for doping control purposes Andre Knoop, Andreas Thomas, Mario Thevis Rapid Communications in Mass Spectrometry November 2018 "... In the field of anti-doping research, the development and improvement of detection methods concerning new substances that potentially exhibit performance-enhancing properties is of utmost importance ... For method development and validation, commercially available pooled human plasma (male AB plasma in K2EDTA) and human serum TYPE AB (male) from Innovative Research,...

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Identification of Receptor Ligands in Apo B100 Reveals Potential Functional Domains

Posted by Leanne Kodsman on

Identification of Receptor Ligands in Apo B100 Reveals Potential Functional Domains

Single Donor Human Plasma from Innovative Research was recently used in the following study: Identification of Receptor Ligands in Apo B100 Reveals Potential Functional Domains Juan Guevara Jr., Jamie Romo Jr., Ernesto Hernandez, Natalia Valentinova Guevara The Protein Journal, 26 September 2018 "... The actual receptor ligand(s) in apolipoprotein B100, one of the main proteins of LLP, remain(s) unknown. The objective of this study was to identify true receptor ligand(s) in apo B100, a molecule of 4563 residues... LDL Purification Highly purified preparations of low-density lipoproteins were obtained from single donor human plasma with sodium-EDTA added at time of collection...

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