Product References — Single Donor Human Plasma Whole Blood Derived

Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction

Posted by Corey Marcath on

Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction Amanda M. G. Lobo Igor R. S. Magalhães SSC plus 12/12/2019 “Tafenoquine, a synthetic analogue of primaquine, is a promising agent for the treatment of human malaria since this drug shows better antimalarial activity than primaquine in vitro and short treatment course. There are some methods for the quantification of tafenoquine in plasma, but none uses dispersive-liquid-liquid microextraction, an extraction technique that shows some advantages, such as miniaturization, low cost and high potential for...

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Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry

Posted by Corey Marcath on

Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Bioanalysis of EGFRm inhibitor osimertinib, and its glutathione cycle- and desmethyl metabolites by liquid chromatography-tandem mass spectrometry J.J.M Rood, M.J.van Haren, J.H.Beijnen, R.W.Sparidans Journal of Pharmaceutical and Biomedical Analysis January 2020 “…Osimertinib is a “third-generation’’ oral, irreversible, tyrosine kinase inhibitor. It is used in the treatment of non-small cellular lung carcinoma and spares wild-type EGFR. Due to its reactive nature, osimertinib is, in addition to oxidative routes, metabolized through GSH coupling and subsequent further metabolism of these conjugates. The extent of the non-oxidative metabolism...

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Direct Mass Spectrometry Analysis of Complex Mixtures by Nanoelectrospray with Simultaneous Atmospheric Pressure Chemical Ionization and Electrophoretic Separation Capabilities

Posted by Corey Marcath on

Direct Mass Spectrometry Analysis of Complex Mixtures by Nanoelectrospray with Simultaneous Atmospheric Pressure Chemical Ionization and Electrophoretic Separation Capabilities

Single Donor Human Serum Off The Clot, Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Direct Mass Spectrometry Analysis of Complex Mixtures by Nanoelectrospray with Simultaneous Atmospheric Pressure Chemical Ionization and Electrophoretic Separation Capabilities Dmytro S. Kulyk, Devin J. Swiner, Taghi Sahraeian, and Abraham K. Badu-Tawiah Analytical Chemistry August 26, 2019 “Accurate and rapid analysis of complex microsamples are challenging tasks in translational research. Nanoelectrospray ionization (nESI) is the method of choice for analyzing small sample volumes by mass spectrometry (MS), but this technique works well only for polar analytes. Herein, we...

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Mathematical model of thrombin generation and bleeding phenotype in Amish carriers of Factor IX:C deficiency vs. controls

Posted by Corey Marcath on

Mathematical model of thrombin generation and bleeding phenotype in Amish carriers of Factor IX:C deficiency vs. controls

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Mathematical model of thrombin generation and bleeding phenotype in Amish carriers of Factor IX:C deficiency vs. controls S. Guptaa, M.C. Bravob, M. Heimana, C. Nakara, K. Brummel-Ziedinsb , C.H. Millerc, A. Shapiro Thrombosis Research 08 August 2019 “…Hemophilia B (HB) is an X-linked bleeding disorder resulting in a deficiency of FIX:C. Variable FIX:C levels can be seen in carriers within the same pedigree with a unifying mutation …therefore to ensure that other inheritable factors which could potentially impact coagulation did not affect the TG...

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Label-Free Optical Detection of Multiple Biomarkers in Sweat, Plasma, Urine, Saliva

Posted by Corey Marcath on

Label-Free Optical Detection of Multiple Biomarkers in Sweat, Plasma, Urine, Saliva

Single Donor Human Plasma (Blood Derived), Single Donor Human Serum Off The Clot from Innovative Research was used in the following study:   Label-Free Optical Detection of Multiple Biomarkers in Sweat, Plasma, Urine, Saliva Prajokta Ray, Andrew J.Steckl ACS Sensors 22 Mar 2019 ”We report a novel label-free quantitative detection of human performance “stress” biomarkers in different body fluids based on optical absorbance of the biomarkers in the ultraviolet (UV) region. …Human plasma and serum (single donor) were obtained from Innovative Research (Novi, MI)…”   Related products available from Innovative Research also include: Single Donor Human Plasma (Blood Derived) Single...

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