Product References — Single Donor Human Plasma Whole Blood Derived

Soluble Sema4D in Plasma of Head and Neck Squamous Cell Carcinoma Patients is Associated with Underlying Non-Inflamed Tumor Profile

Posted by Adam Awdish on

Soluble Sema4D in Plasma of Head and Neck Squamous Cell Carcinoma Patients is Associated with Underlying Non-Inflamed Tumor Profile

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Soluble Sema4D in Plasma of Head and Neck Squamous Cell Carcinoma Patients is Associated with Underlying Non-Inflamed Tumor Profile Rania H. Younis, Ioana Ghita, Manar Elnaggar, Risa Chaisuparat, Vasileios Ionas Theofilou, Donita Dyalram, Robert A. Ord, Eduardo Davila, Luke J. Tallon, John C. Papadimitriou, Tonya J. Webb, Søren M. Bentzen, and Joshua E. Lubek Frontiers in Immunology March 11, 2021 Semaphorin 4D (Sema4D) is a glycoprotein that is capable of functioning as both a membrane bound protein or as a cleaved soluble protein (sSema4D),...

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Development of a Sensitive Assay to Screen Nanoparticles in vitro for Complement Activation

Posted by Adam Awdish on

Development of a Sensitive Assay to Screen Nanoparticles in vitro for Complement Activation

Single Donor Human Whole Blood, Single Donor Human Plasma (Blood Derived), Single Donor Human Complement Serum, Innovative Grade US Origin Porcine Plasma, and Innovative Grade US Origin Porcine Whole Blood from Innovative Research were used in the following study:   Development of a Sensitive Assay to Screen Nanoparticles in vitro for Complement Activation Nuzhat Maisha, Tobias Coombs, and Erin B. Lavik American Chemical Society July 6, 2020 Nanomedicines are often recognized by the innate immune system as a threat, leading to unwanted clearance due to complement activation. This unwanted reaction not only alters the bioavailability of the therapeutic, but can...

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An miRNA Fingerprint Using Neural-Enriched Extracellular Vesicles from Blood Plasma: Towards a Biomarker for Amyotrophic Lateral Sclerosis/Motor Neuron Disease

Posted by Adam Awdish on

An miRNA Fingerprint Using Neural-Enriched Extracellular Vesicles from Blood Plasma: Towards a Biomarker for Amyotrophic Lateral Sclerosis/Motor Neuron Disease

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   An miRNA Fingerprint Using Neural-Enriched Extracellular Vesicles from Blood Plasma: Towards a Biomarker for Amyotrophic Lateral Sclerosis/Motor Neuron Disease Sandra Anne Banack, Rachael Anne Dunlop and Paul Alan Cox The Royal Society Publishing May 22, 2020 Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) continue to provide challenges for diagnosis since validated diagnostic biomarkers are currently unavailable. Rapid diagnosis and intervention in the disease process could be beneficial in slowing neurodegenerative disease progression as well...

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Statistical optimization and validation of a novel ultra-performance liquid chromatography method for estimation of nintedanib in rat and human plasma

Posted by Corey Marcath on

Statistical optimization and validation of a novel ultra-performance liquid chromatography method for estimation of nintedanib in rat and human plasma

Single Donor Human Plasma (Blood Derived) and Innovative Grade US Origin Rat Sprague Dawley Single Donor Plasma from Innovative Research was used in the following study:   Statistical optimization and validation of a novel ultra-performance liquid chromatography method for estimation of nintedanib in rat and human plasma Snehal K Shukla, Hossam Kadry, Jayshil A Bhatt, Rasha Elbatanony, Fakhrul Ahsan & Vivek Gupta Future Science 13 Feb 2020 “A high throughput ultra-performance liquid chromatography (UPLC)-ultraviolet method for quantification of nintedanib in rat and human plasma was developed and optimized using chemometrical approach… Rat plasma and human plasma were acquired from Innovative...

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Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction

Posted by Corey Marcath on

Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction Amanda M. G. Lobo Igor R. S. Magalhães SSC plus 12/12/2019 “Tafenoquine, a synthetic analogue of primaquine, is a promising agent for the treatment of human malaria since this drug shows better antimalarial activity than primaquine in vitro and short treatment course. There are some methods for the quantification of tafenoquine in plasma, but none uses dispersive-liquid-liquid microextraction, an extraction technique that shows some advantages, such as miniaturization, low cost and high potential for...

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