Product References — ELISA Kit

Revolutionizing Diabetes Treatment: Genetically Engineered Pseudo-Islets Achieve Insulin Independence

Posted by Adam Awdish on

Revolutionizing Diabetes Treatment: Genetically Engineered Pseudo-Islets Achieve Insulin Independence

In a groundbreaking study, researchers have pioneered a diabetes treatment that could revolutionize the management of type 1 diabetes. By transplanting genetically engineered hypoimmune pseudo-islets into diabetic non-human primates, the team achieved insulin independence without necessitating immunosuppression, marking a significant advancement in diabetes research. Notably, Molecular Innovations' Total Rhesus IgG ELISA Kit played a crucial role in this research, underscoring the company's commitment to supporting scientific breakthroughs.   The Study's Significance and Methodology The study demonstrates a novel approach to diabetes treatment, utilizing hypoimmune pseudo-islets to circumvent the challenges associated with allogeneic transplantation and immunosuppression. This method not only promises...

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Factor VII Activating Protease (FSAP) Inhibits the Outcome of Ischemic Stroke in Mouse Models

Posted by Adam Awdish on

Factor VII Activating Protease (FSAP) Inhibits the Outcome of Ischemic Stroke in Mouse Models

Mouse Total Fibrinogen ELISA Kit from Innovative Research was used in the following study:   Factor VII Activating Protease (FSAP) Inhibits the Outcome of Ischemic Stroke in Mouse Models Jeong Yeon Kim, Dipankar Manna, Trygve B. Leergaard, Sandip M. Kanse bioRxiv January 12, 2022 Factor VII activating protease (FSAP) is a serine protease associated with cell adhesion, and patients diagnosed with the Marburg I (MI) single nucleotide polymorphism (SNP) have an increased chance of stroke due to inactivation of the FSAP enzyme. Observations in both human patients that have suffered a stroke and in vitro mouse models have shown raised plasma FSAP...

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The Impact of Age and BMI on the VWF/ADAMTS13 Axis and Simultaneous Thrombin and Plasmin Generation in Hospitalized COVID-19 Patients

Posted by Adam Awdish on

The Impact of Age and BMI on the VWF/ADAMTS13 Axis and Simultaneous Thrombin and Plasmin Generation in Hospitalized COVID-19 Patients

Human Total Factor VIII ELISA Kit from Innovative Research was used in the following study:   The Impact of Age and BMI on the VWF/ADAMTS13 Axis and Simultaneous Thrombin and Plasmin Generation in Hospitalized COVID-19 Patients Kiruphagaran Thangaraju, Upendra Katneni, Imo J. Akpan, Kenichi Tanaka, Tiffany Thomas, Saini Setua, Julie A. Reisz, Francesca Cendali, Fabia Gamboni, Travis Nemkov, Stacie Kahn, Alexander Z. Wei, Jacob E. Valk, Krystalyn E. Hudson, David J. Roh, Chiara Moriconi, James C. Zimring, Angelo D'Alessandro, Steven L. Spitalnik, Richard O. Francis, and Paul W. Buehler Frontiers in Medicine January 10, 2022 COVID-19 infection results in a...

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Stability of Alteplase for Ultrasound-Facilitated Catheter-Directed Thrombolysis

Posted by Adam Awdish on

Stability of Alteplase for Ultrasound-Facilitated Catheter-Directed Thrombolysis

Human tPA ELISA Kit from Innovative Research was used in the following study:   Stability of Alteplase for Ultrasound-Facilitated Catheter-Directed Thrombolysis John Fanikos, Kathleen Marquis, Leo Buckley, Lena K. Tran, Kevin McLaughlin, Abby Jane Golash, Umberto Campia, Gregory Piazza, Jean M. Connors, Samuel Z. Goldhaber Blood Advances December 8, 2021 Ultrasound-facilitated catheter-directed thrombolysis (USCDT) is a form of treatment for pulmonary embolism that may minimize the effects of major bleeding complications during treatment. USCDT typically uses low-dose alteplase over the course of up to 8 hours, as major bleeding complications usually result from the administration of high doses of alteplase...

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Hyperglycemia Potentiates Prothrombotic Effect of Aldosterone in a Rat Arterial Thrombosis Model

Posted by Adam Awdish on

Hyperglycemia Potentiates Prothrombotic Effect of Aldosterone in a Rat Arterial Thrombosis Model

Rat Active tPA ELISA Kit and Rat Active PAI-1 ELISA Kit from Innovative Research were used in the following study:   Hyperglycemia Potentiates Prothrombotic Effect of Aldosterone in a Rat Arterial Thrombosis Model Anna Gromotowicz-Poplawska, Piotr Szoka, Agnieszka Zakrzeska, Patrycjusz Kolodziejczyk, Natalia Marcinczyk, Janusz Szemraj, Piotr Tutka, and Ewa Chabielska Cells February 22, 2021 According to evidence gathered in studies over recent years, there appears to be a link between the activation of the renin–angiotensin–aldosterone system (RAAS) and potentially severe cardiovascular problems. The primary process responsible for these cardiac events is acute intravascular arterial thrombosis. The final product of the...

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