Product References — Pooled Human Serum Off The Clot

A proteome-wide screen of Campylobacter jejuni using protein microarrays identifies novel and conformational antigens

Posted by Leanne Kodsmann on

A proteome-wide screen of Campylobacter jejuni using protein microarrays identifies novel and conformational antigens

Pooled Human Serum from Innovative Research was used in the following study:   A proteome-wide screen of Campylobacter jejuni using protein microarrays identifies novel and conformational antigens Jiayou Liu, Jodi R. Parrish, Julie Hines, Linda Mansfield, Russell L. Finley Jr. PLOS | ONE Published: January 11, 2019 "... Mouse antiserum was from mice orally challenged with C. jejuni strain NCTC11168 (24 days post infection) as described [45]. Pooled human sera from 10 healthy individuals (cat. no. IPLA-SER) was obtained from Innovative Research (Novi, MI). Purified GST [46] was used as standard ..."   Related products available from Innovative Research also...

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Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform

Posted by Leanne Kodsmann on

Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform

Human Whole Blood, Pooled Human Serum, and Pooled Human Plasma from Innovative Research were used in the following study:   Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform Christopher R. Phaneuf, Kyle J. Seamon, Tyler P. Eckles, Anchal Sinha, Joseph S. Schoeniger, Brooke Harmon, Robert J. Meagher, Vinay V. Abhyankar and Chung-Yan Koh Analytical Methods Issue 5, 2019 "... The potential for accidental exposure, malicious use, or undesirable persistence of Cas9 therapeutics and off-target genome effects highlight the need for detection assays. Here we report a centrifugal microfluidic platform for the measurement of both Cas9 protein levels and nuclease...

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Supramolecular Polymeric Assemblies for the Selective Depletion of Abundant Acidic Proteins in Serum

Posted by Leanne Kodsmann on

Supramolecular Polymeric Assemblies for the Selective Depletion of Abundant Acidic Proteins in Serum

Pooled Human Serum from Innovative Research was used in the following study:   Supramolecular Polymeric Assemblies for the Selective Depletion of Abundant Acidic Proteins in Serum Mahalia A. C. Serrano, Jingjing Gao, Katrina A. Kelly, Sankaran Thayumanavan, and Richard W. Vachet ACS: Applied Materials & Interfaces Biological and Medical Applications of Materials & Interfaces, Nov 2018 "... The analysis of low-level protein biomarkers in serum is precluded by the presence of other highly abundant serum proteins. Hence, the preliminary removal of serum albumin along with other abundant proteins in serum (i.e. immunoglobulins, transferrin, haptoglobin, alpha-2-macroglobulin and apolipoproteins), is often a...

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Development of novel aptamers for low-density lipoprotein particle quantification

Posted by Leanne Kodsmann on

Development of novel aptamers for low-density lipoprotein particle quantification

Pooled Human Serum from Innovative Research was used in the following study:   Development of novel aptamers for low-density lipoprotein particle quantification Daniel Klapak, Sarah Broadfoot, Gregory Penner Anup Singh, Eshwar Inapuri PLOS|ONE, October 2018 "... LDL particles were isolated from normal pooled human serum (Innovative Research, Novi, MI) using an established ultracentrifugation protocol [19]. Briefly, three different density solutions (1.006 g/mL, 1.02 g/mL and 1.065 g/mL) of KBR were prepared to enable the separation of the two layers of LDL (LF- and SD-LDL), which fall at the junction between each layer. The visualization (Fig 1) of the LDL heterogeneity was...

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Enhancing Treatment Efficacy of 177Lu-PSMA-617 with the Conjugation of an Albumin-Binding Motif: Preclinical Dosimetry and Endoradiotherapy Studies

Posted by Leanne Kodsman on

Human Serum from Innovative Research was recently used in the following study: Enhancing Treatment Efficacy of 177Lu-PSMA-617 with the Conjugation of an Albumin-Binding Motif: Preclinical Dosimetry and Endoradiotherapy StudiesHsiou-Ting Kuo, Helen Merkens, Zhengxing Zhang, Carlos F. Uribe, Joseph Lau, Chengcheng Zhang , Nadine Colpo , Kuo-Shyan Lin , and François Bénard Molecular Pharmaceutics, September 2018 "... All chemicals and solvents were obtained from commercial sources, and used without further purification. Human serum for protein binding assay was obtained from Innovative Research (Novi, MI)... Plasma protein binding assays were performed according to literature methods Briefly, 37 kBq of 177Lu-PSMA-617 or 177Lu-HTK01169...

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