Product References — Pooled Human Serum Off The Clot
Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins
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Pooled Human Urine and Pooled Human Serum Off The Clot from Innovative Research was used in the following study: Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins Alex J. Rai Kevin A. Schug, Katarína Maráková Journal of Separation Science 2/7/2020 “In biological systems, variable protein expression is a crucial marker for numerous diseases, including cancer. The vast majority of liquid chromatography–triple quadrupole mass spectrometry-based quantitative protein assays use bottom-up methodologies, where proteins are subjected to proteolytic cleavage prior to analysis. …As biological...
Validation of a Sensitive UHPLC-MS/MS Method for Cytochrome P450 Probe Substrates Caffeine, Tolbutamide, Dextromethorphan, and Alprazolam in Human Serum Reveals Drug Contamination of Serum Used for Research
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Pooled Human Serum Off The Clot, Single Donor Human Serum Off The Clot from Innovative Research was used in the following study: Validation of a Sensitive UHPLC-MS/MS Method for Cytochrome P450 Probe Substrates Caffeine, Tolbutamide, Dextromethorphan, and Alprazolam in Human Serum Reveals Drug Contamination of Serum Used for Research Luying Chen, Richard B. van Breemen Journal of Pharmaceutical and Biomedical Analysis 9 November 2019 “To evaluate the potential for interactions between botanical dietary supplements and drug metabolism, Phase I clinical pharmacokinetics studies are conducted using an oral cocktail of probe substrates of cytochrome P450 (CYP) enzymes. A sensitive, specific,...
An inherent T cell deficit in healthy males to C. neoformans infection may begin to explain the sex susceptibility in incidence of cryptococcosis
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Pooled Human Serum Off The Clot from Innovative Research was used in the following study: An inherent T cell deficit in healthy males to C. neoformans infection may begin to explain the sex susceptibility in incidence of cryptococcosis Tiffany E. Guess, Joseph Rosen, Natalia Castro-Lopez, Floyd L. Wormley Jr, Erin E. McClelland Biology of Sex Differences 02 September 2019 “…Cryptococcus neoformans is responsible for an estimated 220,000 cases of cryptococcosis, resulting in more than 181,000 deaths each year worldwide. An opportunistic fungal pathogen, C. neoformans typically presents as pneumonia or meningitis, the latter of which is considered an AIDS-defining...
Platelet Factor 4 as a Novel Exosome Marker in MALDI-MS Analysis of Exosomes from Human Serum
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Pooled Human Serum Off The Clot from Innovative Research was used in the following study: Platelet Factor 4 as a Novel Exosome Marker in MALDI-MS Analysis of Exosomes from Human Serum Huu-Quang Nguyen, Dabin Lee, Yeoseon Kim, Minseok Paek, Minsun Kim, Kyoung-Soon Jang, Jooyeon Oh, Young-Sun Lee, Jong Eun Yeon, David M. Lubman, and Jeongkwon Kim Analytical Chemistry September 24, 2019 “…Exosomes are nanosized vesicles commonly found in biological fluids as a result of a secretion process involving endosomes and multivesicular bodies. The isolation and analysis of exosomes can be useful for noninvasive clinical diagnosis of a variety of...
Biomarkers and label-free nucleic acid biomarker detection in cancer and other diseases
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Pooled Human Serum Off The Clot, Single Donor Human Lung Cancer Serum from Innovative Research was used in the following study: Biomarkers and label-free nucleic acid biomarker detection in cancer and other diseases Kim, Hyesook Detroit R&D Inc 07/25/2019 “…The present invention provides a method of obtaining miRNA biomarkers by data-search of up-regulated microRNAs (miRNAs) in cancer and screening the miRNA biomarkers to identify cancer kind- and stage-specific miRNA biomarker(s) using cancer cells, tissues and biological fluids... 5A and 5B show levels of miR29c (Sequence 3) in serum samples obtained from healthy subjects (pooled serum sample, control) and a...