Product References — Human Biological Fluids

Human Factor X Purified from Innovative Research was used in the following study:   Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays M. F. A. Karel, T. P. Lemmens, B. M. E. Tullemans, S. J. H. Wielders, E. Gubbins, D. Van Beurden, S. Van Rijt, and J. M. E. M. Cosemans Cellular and Molecular Bioengineering October 11, 2021 Atherothrombotic events, such as stroke or myocardial infarction, caused by plaque disruption resulting in the exposure of plaque constituents to blood remain a major cause of death in the western world to this day. The combination of plaque constituents and flowing...

Pooled Human Charcoal Dextran Stripped Serum from Innovative Research was used in the following study:   Estrogenic Activity of Mycoestrogen (3β,5α,22E)-Ergost-22-en-3-ol via Estrogen Receptor α-Dependent Signaling Pathways in MCF-7 Cells Dahae Lee, Yuri Ko, Changhyun Pang, Yoon-Joo Ko, You-Kyoung Choi, Ki Hyun Kim, and Ki Sung Kang Molecules December 22, 2021 Estrogen replacement therapy has commonly been used as a treatment for the relief and prevention of postmenopausal symptoms and other similar diseases. Unfortunately, long-term patients receiving estrogen therapy are often reluctant to continue their treatment due to the risk of serious side effects including breast cancer, heart disease, and...

Single Donor Human Complement Serum from Innovative Research was used in the following study:   Cytoprotective IgG Antibodies in Sera from a Subset of Patients with AQP4‑IgG Seropositive Neuromyelitis Optica Spectrum Disorder LukmaneeTradtrantip, Michael R. Yeaman & A. S. Verkman Scientific Reports November 9, 2021 Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disorder that attacks the central nervous system and can cause demyelination in the optic nerve, spinal cord, and brain, and potentially cause further neurological deficits. Over 70% of patients suffering from NMOSD are seropositive for IgG autoantibodies which target extracellular epitopes of astrocyte water channel aquaporin-4 (AQP4),...

Pooled Human Urine from Innovative Research was used in the following study:   Reagent Filming for Universal Point-of-Care Diagnostics Gyeo-Re Han, Hyungjun Jang, Hangil Ki, Hoyeon Lee, and Min-Gon Kim Small Methods 2021 Global medical centers, especially places like outdoor clinics and community health centers, benefit from simplified and decentralized point-of-care testing (POCT) due to their affordability, accessibility, and ease of operation. These factors allow for disease diagnosis in resource-limited settings or in uncontrolled environments, such as field clinics in catastrophe or poverty-affected regions. Simplifying assays, however, comes with its own set of challenges to overcome. For example, translating more...

Human Factor XII Purified, Human Kallikrein Purified, and Human Prekallikrein Purified from Molecular Innovations were used in the following study:   Identification of the Factor XII Contact Activation Site Enables Sensitive Coagulation Diagnostics Marco Heestermans, Clément Naudin, Reiner K. Mailer, Sandra Konrath, Kristin Klaetschke, Anne Jämsä, Maike Frye, Carsten Deppermann, Giordano Pula, Piotr Kuta, Manuel A. Friese, Mathias Gelderblom, Albert Sickmann, Roger J. S. Preston, Jerzy-Roch Nofer, Stefan Rose-John, Lynn M. Butler, Ophira Salomon, Evi X. Stavrou, and Thomas Renné Nature Communications September 22, 2021 Blood coagulation is an essential part of stopping bleeding at the site of vascular injuries....