Product References — Human Biological Fluids

Single Donor Human Platelets ACD from Innovative Research was used in the following study:   Near-Infrared-Driven Photoablation of Lung Cancer Tumors Utilizing Biomimetic Platelet-Polyethyleneimine-Polypyrrole Drug-Free Nanoparticles Burnouf, T.; Jheng, P-R.; Chen, Y-H.; Rethi, L.; Rethi, L.; Lu, L-S.; Ho, Y-C.; Chuang, E-Y. Materials & Design February 20, 2022 In the field of cancer treatment, intraperitoneal (IP) administration can be used to deliver drugs to a patient, however, it doesn’t distinguish between tumors and healthy tissues, opening the potential for harm to healthy organs during treatment. One of several newer approaches to cancer treatment, photothermal therapy (PTT), is currently a topic...

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   The Binding Mechanisms of Antibodies to DNA from Healthy Subjects and Patients with Systemic Lupus Erythematosus: The Role of Monogamous Bivalency and Fc Dependence Morgan E. Belina, Diane M. Spencer, and David S. Pisetsky ImmunoHorizons February 1, 2022 Antibodies that target DNA (anti-DNA) are a unique subset of antibodies which bind to the structural components of DNA molecules. They were originally observed within the context of systemic lupus erythematosus (SLE), and anti-DNA in SLE appeared to have the ability to bind DNA regardless of...

Human Factor X Purified from Innovative Research was used in the following study:   Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays M. F. A. Karel, T. P. Lemmens, B. M. E. Tullemans, S. J. H. Wielders, E. Gubbins, D. Van Beurden, S. Van Rijt, and J. M. E. M. Cosemans Cellular and Molecular Bioengineering October 11, 2021 Atherothrombotic events, such as stroke or myocardial infarction, caused by plaque disruption resulting in the exposure of plaque constituents to blood remain a major cause of death in the western world to this day. The combination of plaque constituents and flowing...

Pooled Human Charcoal Dextran Stripped Serum from Innovative Research was used in the following study:   Estrogenic Activity of Mycoestrogen (3β,5α,22E)-Ergost-22-en-3-ol via Estrogen Receptor α-Dependent Signaling Pathways in MCF-7 Cells Dahae Lee, Yuri Ko, Changhyun Pang, Yoon-Joo Ko, You-Kyoung Choi, Ki Hyun Kim, and Ki Sung Kang Molecules December 22, 2021 Estrogen replacement therapy has commonly been used as a treatment for the relief and prevention of postmenopausal symptoms and other similar diseases. Unfortunately, long-term patients receiving estrogen therapy are often reluctant to continue their treatment due to the risk of serious side effects including breast cancer, heart disease, and...

Single Donor Human Complement Serum from Innovative Research was used in the following study:   Cytoprotective IgG Antibodies in Sera from a Subset of Patients with AQP4‑IgG Seropositive Neuromyelitis Optica Spectrum Disorder LukmaneeTradtrantip, Michael R. Yeaman & A. S. Verkman Scientific Reports November 9, 2021 Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disorder that attacks the central nervous system and can cause demyelination in the optic nerve, spinal cord, and brain, and potentially cause further neurological deficits. Over 70% of patients suffering from NMOSD are seropositive for IgG autoantibodies which target extracellular epitopes of astrocyte water channel aquaporin-4 (AQP4),...