Product References — Single Donor Human Serum Off The Clot

An Autoantibody Profile Detects Brugada Syndrome and Identifies Abnormally Expressed Myocardial Proteins

Posted by Adam Awdish on

An Autoantibody Profile Detects Brugada Syndrome and Identifies Abnormally Expressed Myocardial Proteins

Single Donor Human Serum Off The Clot from Innovative Research was used in the following study:   An Autoantibody Profile Detects Brugada Syndrome and Identifies Abnormally Expressed Myocardial Proteins Diptendu Chatterjee, Maurizio Pieroni, Meena Fatah, Flavien Charpentier, Kristopher S Cunningham, Danna A Spears, Dipashree Chatterjee, Gonca Suna, J Martjin Bos, Michael J Ackerman, Eric Schulze-Bahr, Sven Dittmann, Pasquale G Notarstefano, Leonardo Bolognese, Firat Duru, Ardan M Saguner, Robert M Hamilton European Heart Journal August 7, 2020 Brugada syndrome (BrS) is characterized by a unique electrocardiogram (ECG) pattern and life-threatening arrhythmias. However, the Type 1 Brugada ECG pattern is often transient,...

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Validation of a Sensitive UHPLC-MS/MS Method for Cytochrome P450 Probe Substrates Caffeine, Tolbutamide, Dextromethorphan, and Alprazolam in Human Serum Reveals Drug Contamination of Serum Used for Research

Posted by Corey Marcath on

Validation of a Sensitive UHPLC-MS/MS Method for Cytochrome P450 Probe Substrates Caffeine, Tolbutamide, Dextromethorphan, and Alprazolam in Human Serum Reveals Drug Contamination of Serum Used for Research

Pooled Human Serum Off The Clot, Single Donor Human Serum Off The Clot from Innovative Research was used in the following study:   Validation of a Sensitive UHPLC-MS/MS Method for Cytochrome P450 Probe Substrates Caffeine, Tolbutamide, Dextromethorphan, and Alprazolam in Human Serum Reveals Drug Contamination of Serum Used for Research Luying Chen, Richard B. van Breemen Journal of Pharmaceutical and Biomedical Analysis 9 November 2019 “To evaluate the potential for interactions between botanical dietary supplements and drug metabolism, Phase I clinical pharmacokinetics studies are conducted using an oral cocktail of probe substrates of cytochrome P450 (CYP) enzymes. A sensitive, specific,...

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Evaluation of cryopreservation media for the preservation of human corneal stromal stem cells

Posted by Corey Marcath on

Evaluation of cryopreservation media for the preservation of human corneal stromal stem cells

Single Donor Human Serum Off The Clot from Innovative Research was used in the following study:   Evaluation of cryopreservation media for the preservation of human corneal stromal stem cells Yuzhao Sun, Aurelie Dos Santos, Alis Balayan, Sophie X. Deng Tissue Engineering December 5, 2019 ”…Human corneal stromal stem cells (CSSCs) have gained increasing attention in the treatment of corneal stromal scars. In view of this, the preparation and storage of CSSCs are critical to maintaining the regenerative potential of CSSCs. The goal of the study was to investigate the human serum (HS) concentration in the cryomedia that could best...

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Direct Mass Spectrometry Analysis of Complex Mixtures by Nanoelectrospray with Simultaneous Atmospheric Pressure Chemical Ionization and Electrophoretic Separation Capabilities

Posted by Corey Marcath on

Direct Mass Spectrometry Analysis of Complex Mixtures by Nanoelectrospray with Simultaneous Atmospheric Pressure Chemical Ionization and Electrophoretic Separation Capabilities

Single Donor Human Serum Off The Clot, Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Direct Mass Spectrometry Analysis of Complex Mixtures by Nanoelectrospray with Simultaneous Atmospheric Pressure Chemical Ionization and Electrophoretic Separation Capabilities Dmytro S. Kulyk, Devin J. Swiner, Taghi Sahraeian, and Abraham K. Badu-Tawiah Analytical Chemistry August 26, 2019 “Accurate and rapid analysis of complex microsamples are challenging tasks in translational research. Nanoelectrospray ionization (nESI) is the method of choice for analyzing small sample volumes by mass spectrometry (MS), but this technique works well only for polar analytes. Herein, we...

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Differentiation of 2‐hydroxyglutarate enantiomers and its lactones by gas chromatography/electron ionization tandem mass spectrometry

Posted by Corey Marcath on

Differentiation of 2‐hydroxyglutarate enantiomers and its lactones by gas chromatography/electron ionization tandem mass spectrometry

Single Donor Human Serum Off The Clot from Innovative Research was used in the following study:   Differentiation of 2‐hydroxyglutarate enantiomers and its lactones by gas chromatography/electron ionization tandem mass spectrometry Shinji K. Strain, Morris D. Groves, Mark R. Emmett Rapid Communications in Mass Spectrometry 11 May 2019 “…2‐Hydroxyglutaric acid (2‐hg) is a dicarboxylic acid with a hydroxyl group at the alpha carbon, forming the enantiomers (R)‐2‐ hydroxyglutaric acid (R‐2‐hg) (Figure 1A) and (S)‐2‐hydroxyglutaric acid (S‐2‐hg) (Figure 1B).1 Though detectable in normal tissues, the detection of 2‐hg enantiomers in bodily fluids first gained traction in patients with 2‐hydroxyglutaric acidurias, a...

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