Integrated Dielectrophoretic and Impedimetric Biosensor Provides a Template for Universal Biomarker Sensing in Clinical Samples

Integrated Dielectrophoretic and Impedimetric Biosensor Provides a Template for Universal Biomarker Sensing in Clinical Samples

Posted by Adam Awdish on

Single Donor Human Serum Off The Clot from Innovative Research was used in the following study:

 

Integrated Dielectrophoretic and Impedimetric Biosensor Provides a Template for Universal Biomarker Sensing in Clinical Samples

Logeeshan Velmanickam, Vidura Jayasooriya, Dharmakeerthi Nawarathna

Electrophoresis
January 20, 2021

The use of circulating biomarker tests is common in the screening and diagnosis of various diseases and infections. These tests commonly target biomarkers such as DNA, miRNA, and proteins, however, these different molecules all require different testing procedures and assays which increase the time and costs associated with diagnosis. Miniaturized testing devices have been utilized as a faster and cheaper alternative to standard versions of testing assays, however these miniaturized versions still suffer from the same issue of low sensitivity as the tests they were derived from.

The researchers in this experiment developed and tested a disposable universal point-of-care biosensor designed to detect and quantify nucleic acid and proteomic biomarkers in serum. The sensor relies on dielectrophoresis, electrothermal effects, and thermophoresis to rapidly isolate biomarkers of interest and quantify them via electrical impedance. Observations showed the sensor exhibit a promising degree of sensitivity, and the test can be performed at a low cost and in under 30 minutes.

 

Related products available from Innovative Research also include:

Pooled Human Serum Off The Clot

Single Donor Human Plasma (Blood Derived)

Single Donor Human Whole Blood

  • Tags: Human Serum, Single Donor Human Serum Off The Clot

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