Product References — Human Blood Cells

Coupling Fluorescence-Activated Cell Sorting and Targeted Analysis of Histone Modification Profiles in Primary Human Leukocytes

Posted by Corey Marcath on

Coupling Fluorescence-Activated Cell Sorting and Targeted Analysis of Histone Modification Profiles in Primary Human Leukocytes

Single Donor Human Buffy Coats Leukocytes from Innovative Research was used in the following study:   Coupling Fluorescence-Activated Cell Sorting and Targeted Analysis of Histone Modification Profiles in Primary Human Leukocytes Jeannie M. Camarillo, Suchitra Swaminathan, Nebiyu A. Abshiru, Jacek W. Sikora, Paul M. Thomas, Neil L. Kelleher Journal of The American Society for Mass Spectrometry 08 July 2019 “…Histone posttranslational modifications (PTMs) are essential for regulating chromatin and maintaining gene expression throughout cell differentiation. Despite the deep level of understanding of immunophenotypic differentiation pathways in hematopoietic cells, few studies have investigated global levels of histone PTMs required for differentiation...

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Reduction of Blood Volume Required to Perform Paper-Based Hematocrit Assays Guided by Device Design

Posted by Corey Marcath on

Reduction of Blood Volume Required to Perform Paper-Based Hematocrit Assays Guided by Device Design

Single Donor Human Red Blood Cells Washed from Innovative Research was used in the following study:   Reduction of Blood Volume Required to Perform Paper-Based Hematocrit Assays Guided by Device Design Syrena C. Fernandes, Keith R. Baillargeon, and Charles R. Mace Analytical Methods 22 Mar 2019 ”Point-of-care diagnostic tests can provide rapid and accurate information about the health of a patient without relying on the expensive equipment found in centralized laboratories. Not only does the development and application of these assays rely on the means of signal transduction, but also the method by which a sample is procured. …We obtained...

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Presence of Round Cells Proteins do not Interfere with Identification of Human Sperm Proteins from Frozen Semen Samples by LC-MS/MS

Posted by Leanne Kodsmann on

Presence of Round Cells Proteins do not Interfere with Identification of Human Sperm Proteins from Frozen Semen Samples by LC-MS/MS

Single Donor Human Buffy Coats Leukocytes from Innovative Research was used in the following study:   Presence of Round Cells Proteins do not Interfere with Identification of Human Sperm Proteins from Frozen Semen Samples by LC-MS/MS Manesh Kumar Panner Selvam, Ashok Agarwal, Tânia R. Dias, Ana D. Martins and Luna Samanta International Journal of Molecular Sciences 2019 Volume 20, Issue 2 "... Based on the concentration of round cells and leukocytes, and the sample processing, the experimental groups were defined as follows: Group 1 contained neat semen with round cells and leukocytes ≥ 1 × 10^6/mL; group 2 contained neat...

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Antibacterial isoamphipathic oligomers highlight the importance of multimeric lipid aggregation for antibacterial potency

Posted by Leanne Kodsmann on

Antibacterial isoamphipathic oligomers highlight the importance of multimeric lipid aggregation for antibacterial potency

Human Red Blood Cells from Innovative Research were used in the following study:   Antibacterial isoamphipathic oligomers highlight the importance of multimeric lipid aggregation for antibacterial potency Joseph S. Brown, Zeinab J. Mohamed, Christine M. Artim, Dana N. Thornlow, Joseph F. Hassler, Vincent P. Rigoglioso, Susan Daniel & Christopher A. Alabi Communications Biology volume 1, Article number: 220 (2018) "... This work has focused on the development of new experimental parameters for membrane-targeting antimicrobials, outside of the known properties of cationic charge and hydrophobicity. OligoTEAs have enabled the synthesis of isoamphipathic oligomers to specifically probe additional parameters in membrane disruption....

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Synthesis of Lysine Mimicking Membrane Active Antimicrobial Polymers

Posted by Leanne Kodsmann on

Synthesis of Lysine Mimicking Membrane Active Antimicrobial Polymers

Single Donor Human Red Blood Cells from Innovative Research was used in the following study:   Synthesis of Lysine Mimicking Membrane Active Antimicrobial Polymers Ankita Arora, Wan Zheng, Hongjun Liang, Abhijit Mishra Advances in Polymer Sciences and Technology Materials Horizons: From Nature to Nanomaterials (2018). "... In this study, we synthesize lysine mimicking homopolymer and lysine mimicking copolymer with hydrophobic group and study their antimicrobial activity against both Gram-positive and Gram-negative bacteria. The advantage of using such antibiotic polymers over conventional AMPs is their scalability, cost-effectiveness and chemical stability in in vivo environment ... Fresh human red blood cell (HRBC)...

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