Product References — Antibodies

Contribution of Coagulases towards Staphylococcus aureus Disease and Protective Immunity

Posted by Adam Awdish on

Contribution of Coagulases towards Staphylococcus aureus Disease and Protective Immunity

Human Factor II (Prothrombin) Purified, Human Fibrinogen Purified, and Rabbit Anti Mouse/Rat Fibrinogen Polyclonal Affinity Purified from Innovative Research were used in the following study:   Contribution of Coagulases towards Staphylococcus aureus Disease and Protective Immunity Alice G. Cheng, Molly McAdow, Hwan K. Kim, Taeok Bae, Dominique M. Missiakas, Olaf Schneewind PLOS Pathogens August 5, 2010 Staphylococcus aureus is a bacterium responsible for many common infections, including bacteremia, pneumonia, soft tissue infections, and septic arthritis among others. There remains no known way to gain protective immunity against S. aureus diseases, and researchers continue to investigate options for an effective vaccine....

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Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib

Posted by Adam Awdish on

Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib

Rabbit Anti Mouse Antiplasmin Polyclonal Fractionated HRP Labeled from Innovative Research was used in the following study:   Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib Yusuke Yamashita, Shuhei Morita, Hiroki Hosoi, Hiroshi Kobata, Shohei Kishimoto, Tatsuya Ishibashi, Hiroyuki Mishima, Akira Kinoshita, Bradley J. Backes, Koh-Ichiro Yoshiura, Feroz R. Papa, Takashi Sonoki, and Shinobu Tamura International Journal of Molecular Sciences August 31, 2020 Inositol-requiring enzyme 1α (IRE1α) and protein kinase R-like endoplasmic reticulum kinase (PERK) are key regulators of the unfolded protein response (UPR). The UPR is a cellular mechanism that helps...

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Hydrogen sulfide donor NaHS alters antibody structure and function via sulfhydration

Posted by Corey Marcath on

Hydrogen sulfide donor NaHS alters antibody structure and function via sulfhydration

Rabbit IgG Affinity Purified from Innovative Research was used in the following study:   Hydrogen sulfide donor NaHS alters antibody structure and function via sulfhydration Zhang Z, Fang X, Yang X, Mitsui T, Huang Y, Mao Z, Huang Y, Takeda M, Yao J. International Immunopharmacology 2019 Jun 4 ”…Hydrogen sulfide (H2S) is an endogenous gaseous mediator, which is produced by many tissues and organs. It has a wide range of physiological functions, including acting as a neurotransmitter, relaxing the blood vessels, regulating blood pressure, scavenging reactive oxygen species and protecting cells against oxidative stress. …Protein Apurified rabbit IgG was obtained...

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B- and T-lymphocyte attenuator stimulation protects against atherosclerosis by regulating follicular B cells

Posted by Corey Marcath on

B- and T-lymphocyte attenuator stimulation protects against atherosclerosis by regulating follicular B cells

Hamster Armenian IgG Affinity Purified from Innovative Research was used in the following study:   B- and T-lymphocyte attenuator stimulation protects against atherosclerosis by regulating follicular B cells Hidde Douna, Jacob Amersfoort, Frank H. Schaftenaar, Mara J. Kro¨ ner, Ma´te´ G. Kiss, Bram Slu¨ tter, Marie A. C. Depuydt, Mireia N. A. Bernabe´ Kleijn, Anouk Wezel, Harm J. Smeets, Hideo Yagita, Christoph J. Binder, I. Bot, Gijs H. M. van Puijvelde, Johan Kuiper, and Amanda C. Foks European Society of Cardiology 10 May 2019 “…Inflammation is a key process in the development of atherosclerosis. Components of both the innate and...

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Acute activation of endothelial AMPK surprisingly inhibits endothelium‐dependent hyperpolarization‐like relaxations in rat mesenteric arteries

Posted by Corey Marcath on

Acute activation of endothelial AMPK surprisingly inhibits endothelium‐dependent hyperpolarization‐like relaxations in rat mesenteric arteries

Goat Anti Rabbit IgG Polyclonal Affinity Purified Immunoadsorbed HRP Labeled from Innovative Research was used in the following study:   Acute activation of endothelial AMPK surprisingly inhibits endothelium‐dependent hyperpolarization‐like relaxations in rat mesenteric arteries Hui Chen, Paul M. Vanhoutte, Susan W.S. Leung British Pharmacological Society 8 May 2019 “…Endothelium‐dependent relaxations of isolated arteries have been attributed to either the release of diffusible mediators (NO and prostacyclin) or the generation of endothelium‐dependent hyperpolarization (EDH) signals (Leung & Vanhoutte, 2015; …Anti‐rabbit (Innovative Research Cat# 62‐6120, RRID:AB_88349) and anti‐mouse (GE Healthcare Cat# NA931, RRID:AB_772210) IgG secondary antibodies were purchased from Innovative Research (Novi,...

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