Product References — Pooled Human Plasma Plasma Off The Clot

α-Synuclein in Blood Exosomes Immunoprecipitated Using Neuronal and Oligodendroglial Markers Distinguishes Parkinson’s Disease from Multiple System Atrophy

Posted by Adam Awdish on

α-Synuclein in Blood Exosomes Immunoprecipitated Using Neuronal and Oligodendroglial Markers Distinguishes Parkinson’s Disease from Multiple System Atrophy

Pooled Human Plasma (Blood Derived) and Pooled Human Serum Off the Clot from Innovative Research were used in the following study:   α-Synuclein in Blood Exosomes Immunoprecipitated Using Neuronal and Oligodendroglial Markers Distinguishes Parkinson’s Disease from Multiple System Atrophy Suman Dutta, Simon Hornung, Adira Kruayatidee, Katherine N. Maina, Irish del Rosario, Kimberly C. Paul, Darice Y. Wong, Aline Duarte Folle, Daniela Markovic, Jose-Alberto Palma, Geidy E. Serrano, Charles H. Adler, Susan L. Perlman, Wayne W. Poon, Un Jung Kang, Roy N. Alcalay, Miriam Sklerov, Karen H. Gylys, Horacio Kaufmann, Brent L. Fogel, Jeff M. Bronstein, Beate Ritz & Gal Bitan...

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Analysis of the Human Plasma Proteome Using Multi‐Nanoparticle Protein Corona for Detection of Alzheimer's Disease

Posted by Adam Awdish on

Analysis of the Human Plasma Proteome Using Multi‐Nanoparticle Protein Corona for Detection of Alzheimer's Disease

Single Donor Human Alzheimer's Plasma and Single Donor Human Plasma (Blood Derived) from Innovative Research were used in the following study:   Analysis of the Human Plasma Proteome Using Multi‐Nanoparticle Protein Corona for Detection of Alzheimer's Disease Claudia Corbo, Andrew A. Li, Hossein Poustchi, Gha Young Lee, Sabrina Stacks, Roberto Molinaro, Philip Ma, Theo Platt, Shahed Behzadi, Robert Langer, Vivek Farias, and Omid C. Farokhzad Advanced Healthcare Materials November 9, 2020 Alzheimer’s disease (AD) is a form of dementia that affects roughly 10% of the population over the age of 65 with the number of diagnosed cases increasing each year. Current...

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Profiling of Cholesteryl Esters by Coupling Charge Tagging Paterno-Buchi Reaction and Liquid Chromatography-Mass Spectrometry

Posted by Adam Awdish on

Profiling of Cholesteryl Esters by Coupling Charge Tagging Paterno-Buchi Reaction and Liquid Chromatography-Mass Spectrometry

Pooled Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Profiling of Cholesteryl Esters by Coupling Charge Tagging Paterno-Buchi Reaction and Liquid Chromatography-Mass Spectrometry Xiaobo Xie, Jing Zhao, Miao Lin, Jinlan Zhang, and Yu Xia Analytical Chemistry May 15, 2020 Cholesteryl esters (CEs) are lipids synthesized from cholesterol by fatty acids and are the preferred method of transporting and storing cholesterol. Although CEs are composed of only two parts (cholesterol and fatty acyl), they can be quite diverse from one another. Due to their diversity, various diseases have been linked to an imbalance between cholesterol...

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HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study

Posted by Leanne Kodsmann on

HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study

Human Plasma from Innovative Research was used in the following study:   HIV Integrase Inhibitor Pharmacogenetics: An Exploratory Study Derek E. Murrell, David B. Cluck, Jonathan P. Moorman, Stacy D. Brown, Ke-Sheng Wang, Michelle M. Duffourc, Sam Harirforoosh Clinical Drug Investigation March 2019, Volume 39, Issue 3, pp 285–299 "... Plasma, for pharmacokinetic analysis, and remaining cells, for genetic testing, were separated then placed at −80 °C until analysis. Samples were analyzed using a previously validated liquid chromatography-mass spectrometry (LC–MS) assay developed by Simiele et al., with modifcations [25]. Briefy, a standard curve ranging from 10 ng/ml to 1500 ng/ml...

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Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform

Posted by Leanne Kodsmann on

Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform

Human Whole Blood, Pooled Human Serum, and Pooled Human Plasma from Innovative Research were used in the following study:   Ultrasensitive multi-species detection of CRISPR-Cas9 by a portable centrifugal microfluidic platform Christopher R. Phaneuf, Kyle J. Seamon, Tyler P. Eckles, Anchal Sinha, Joseph S. Schoeniger, Brooke Harmon, Robert J. Meagher, Vinay V. Abhyankar and Chung-Yan Koh Analytical Methods Issue 5, 2019 "... The potential for accidental exposure, malicious use, or undesirable persistence of Cas9 therapeutics and off-target genome effects highlight the need for detection assays. Here we report a centrifugal microfluidic platform for the measurement of both Cas9 protein levels and nuclease...

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