Product References — Human Serum
A Novel Transgenic Mouse Model for Corneal Scar Visualization
Posted by Adam Awdish on
Pooled Human Serum Off The Clot from Innovative Research was used in the following study: A Novel Transgenic Mouse Model for Corneal Scar Visualization Irona Khandaker, James L. Funderburgh, Moira L. Geary, Martha L. Funderburgh, Vishal Jhanji, Yiqin Du, Gary Hin-Fai Yam Experimental Eye Research September 23, 2020 According to the WHO, vision loss affects over 2.2 billion people globally each year. Corneal opacification resulting from fibrotic scar tissue following infection or injury is a common cause of corneal blindness, and the standard treatment for persistent scar tissue is corneal transplantation of donor tissues. However, there are limitations hindering...
Calvatianone, a Sterol Possessing a 6/5/6/5-Fused Ring System with a Contracted Tetrahydrofuran B‑Ring, from the Fruiting Bodies of Calvatia nipponica
Posted by Adam Awdish on
Pooled Human Charcoal Dextran Stripped Serum from Innovative Research was used in the following study: Calvatianone, a Sterol Possessing a 6/5/6/5-Fused Ring System with a Contracted Tetrahydrofuran B‑Ring, from the Fruiting Bodies of Calvatia nipponica Seulah Lee, Dahae Lee, Rhim Ryoo, Jin-Chul Kim, Hyun Bong Park, Ki Sung Kang, and Ki Hyun Kim Journal of Natural Products September 17, 2020 The Calvatia species of mushrooms, also called puffball mushrooms, have widespread use as food source and medicinal ingredient, particularly in wound dressings. Calvatia nipponica is an extremely rare type of puffball mushroom with a limited number of studies on its chemical and biological functions....
Photoreactive Carboxybetaine Copolymers Impart Biocompatibility and Inhibit Plasticizer Leaching on Polyvinyl Chloride
Posted by Adam Awdish on
Pooled Human Complement Serum from Innovative Research was used in the following study: Photoreactive Carboxybetaine Copolymers Impart Biocompatibility and Inhibit Plasticizer Leaching on Polyvinyl Chloride Xiaojie Lin, Kan Wu, Qiong Zhou, Priyesh Jain, Mary O’Kelly Boit, Bowen Li, Hsiang-Chieh Hung, Sharon A. Creason, Jonathan Himmelfarb, Buddy D. Ratner, and Shaoyi Jiang American Chemical Society September 2, 2020 Medical-grade poly(vinyl chloride) (PVC) is commonly used in flexible medical products because of its transparency, strength, and affordability. Although toxicological, biological, and physiological testing of PVC products has deemed them safe, medical-grade PVC-based materials are criticized for high thrombin generation and complement...
Reduced Red Blood Cell Surface Level of Factor H as a Mechanism Underlying Paroxysmal Nocturnal Hemoglobinuria
Posted by Adam Awdish on
Pooled Human Serum Off The Clot from Innovative Research was used in the following study: Reduced Red Blood Cell Surface Level of Factor H as a Mechanism Underlying Paroxysmal Nocturnal Hemoglobinuria Lingjun Zhang, Jin Y. Chen, Cassandra Kerr, Brian A. Cobb, Jaroslaw P. Maciejewski & Feng Lin Leukemia August 19, 2020 Complement is an important factor in the innate immune response that primarily acts to fight infection and clear apoptotic cells. Once activated, the complement cascade helps in the formation of membrane attack complexes (MAC, C5b-9) on the surfaces of pathogens, causing damage and even lysis of the intruding...
The Safety and Efficacy of Live Viral Vaccines in Patients With Cartilage-Hair Hypoplasia
Posted by Adam Awdish on
Pooled Human AB Serum Off The Clot Heat Inactivated from Innovative Research was used in the following study: The Safety and Efficacy of Live Viral Vaccines in Patients With Cartilage-Hair Hypoplasia Svetlana Vakkilainen, Iivari Kleino, Jarno Honkanen, Harri Salo, Leena Kainulainen, Michaela Gräsbeck, Eliisa Kekäläinen, Outi Mäkitie, and Paula Klemetti Frontiers in Immunology August 11, 2020 Cartilage-hair hypoplasia (CHH) is a rare skeletal dysplasia with combined immunodeficiency that is caused by genetic mutations. The degree of immunodeficiency experienced by patients with CHH can vary greatly, ranging from asymptomatic lymphopenia to severe deficiencies requiring stem cell transplants. Because of this,...