Product References — Human Plasma

A New Promising Anti-Infective Agent Inhibits Biofilm Growth by Targeting Simultaneously a Conserved RNA Function That Controls Multiple Genes

Posted by Adam Awdish on

A New Promising Anti-Infective Agent Inhibits Biofilm Growth by Targeting Simultaneously a Conserved RNA Function That Controls Multiple Genes

Pooled Human Plasma (Blood Derived) from Innovative Research was used in the following study:   A New Promising Anti-Infective Agent Inhibits Biofilm Growth by Targeting Simultaneously a Conserved RNA Function That Controls Multiple Genes Thorsten M. Seyler, Christina Moore, Haein Kim, Sheetal Ramachandran and Paul F. Agris Antibiotics January 4, 2021 An immediate contemporary challenge in the field of medicine is that of combating drug-resistant infections in the form of biofilms. Due to the diverse population of bacteria that can cause infection and their constantly evolving defense mechanisms, there is a lot of focus on developing new treatments that are...

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Interspecies Comparison of Simultaneous Thrombin and Plasmin Generation

Posted by Adam Awdish on

Interspecies Comparison of Simultaneous Thrombin and Plasmin Generation

Pooled Human Plasma (Blood Derived) and Innovative Grade US Origin Rabbit Plasma from Innovative Research was used in the following study:   Interspecies Comparison of Simultaneous Thrombin and Plasmin Generation Ivan D. Tarandovskiy, Hye Kyung H. Shin, Jin Hyen Baek, Elena Karnaukhova & Paul W. Buehler Scientific Reports March 3, 2020 Many fields of basic and pharmaceutical research use animal models of hemostasis and thrombosis and extrapolate the results in humans. However, data from animal models often is not accurate in predicting human responses to various biological factors, and assays provide limited relevant comparisons between human blood and blood of...

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Analysis of the Human Plasma Proteome Using Multi‐Nanoparticle Protein Corona for Detection of Alzheimer's Disease

Posted by Adam Awdish on

Analysis of the Human Plasma Proteome Using Multi‐Nanoparticle Protein Corona for Detection of Alzheimer's Disease

Single Donor Human Alzheimer's Plasma and Single Donor Human Plasma (Blood Derived) from Innovative Research were used in the following study:   Analysis of the Human Plasma Proteome Using Multi‐Nanoparticle Protein Corona for Detection of Alzheimer's Disease Claudia Corbo, Andrew A. Li, Hossein Poustchi, Gha Young Lee, Sabrina Stacks, Roberto Molinaro, Philip Ma, Theo Platt, Shahed Behzadi, Robert Langer, Vivek Farias, and Omid C. Farokhzad Advanced Healthcare Materials November 9, 2020 Alzheimer’s disease (AD) is a form of dementia that affects roughly 10% of the population over the age of 65 with the number of diagnosed cases increasing each year. Current...

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Combined Thrombogenic Effects of Vessel Injury, Pregnancy and Procoagulant Immune Globulin Administration in Mice

Posted by Adam Awdish on

Combined Thrombogenic Effects of Vessel Injury, Pregnancy and Procoagulant Immune Globulin Administration in Mice

Innovative Grade US Origin Mouse C57BL6 Plasma and Pooled Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Combined Thrombogenic Effects of Vessel Injury, Pregnancy and Procoagulant Immune Globulin Administration in Mice Yanqun Xu, Yideng Liang, Leonid Parunov, Daryl Despres, Michael Eckhaus, Dorothy Scott, Mikhail Ovanesov & Evi B. Struble Thrombosis Journal November 7, 2020 Normal pregnancies create hypercoagulable conditions within the body to naturally lower the risk of bleeding during birth. However, the changes observed in the hemostatic system also put pregnant women at risk of various thrombotic events (TEs), such as deep venous...

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Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models

Posted by Adam Awdish on

Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models

Pooled Human Plasma (Blood Derived) from Innovative Research was used in the following study:   Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models Satish Noonepalle, Sida Shen, Jakub Ptáček, Maurício T. Tavares, Guiping Zhang, Jan Stránský, Jiří Pavlíček, Glaucio M. Ferreira, Melissa Hadley, Guido Pelaez, Cyril Bařinka, Alan P. Kozikowski, and Alejandro Villagra Journal of Medicinal Chemistry August 20, 2020 Reversible acetylation of lysine side chains on protein and enzyme surfaces is modulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Acetylation or deacetylation of protein lysine serves...

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