Sugar Shock: Probing Streptococcus Pyogenes Metabolism Through Bioluminescence Imaging
Posted by Adam Awdish on
Innovative Grade US Origin Mouse C57BL6 Plasma from Innovative Research was used in the following study:
Sugar Shock: Probing Streptococcus Pyogenes Metabolism Through Bioluminescence Imaging
Richard W. Davis IV, Charlotte G. Muse, Heather Eggleston, Micaila Hill, Peter Panizzi
bioRxiv
January 16, 2022
Despite having limited use in diagnostic medical settings, light-producing bacterium can be extremely useful in pre-clinical experiments by giving the opportunity to track in real-time the spread of these pathogens throughout the course of an infection. A major limitation to using these pathogens in research, however, is the gap in understanding the changes in light production observed by these microbes. Thus, there is a desire to understand whether the processes are linked to the local environment or are controlled within the microbe, and there is further desire to understand the mechanisms behind these potential pathways.
In this study researchers examined the Streptococcus pyogenes (S. pyogenes) pathogen, as it can thrive in its host during infection. Researchers mapped the central metabolism of the pathogen in response to different environmental triggers to determine whether it responds to external stimuli and carbon availability.
Related products available from Innovative Research also include:
Pooled Human Plasma (Blood Derived)