Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS

Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS

Posted by Corey Marcath on

Pooled Human Plasma Apheresis Derived from Innovative Research was used in the following study:

 

Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS

Christofer A. Q. Karlsson, Sofia Jarnum, Lena Winstedt, Christian Kjellman, Lars Bjorck, Adam Linder‡, Johan A. Malmstro

The American Society for Biochemistry and Molecular Biology
March 6, 2018

”…The molecular interplay between host and pathogen is complex and under considerable evolutionary pressure. Determining the structure, function and dynamics of all host pathogen interactions in a systems-wide and quantitative manner is a formidable and fundamental challenge in medical microbiology. A complicating factor is that many bacterial pathogens can cause diverse clinical manifestations, ranging from superficial to invasive disease, expanding the types of interactions. …Plasma samples from healthy individuals were from (49) (blood collected with vacutainer sodium citrate tubes) or were purchased from Innovative Research (pooled normal human plasma, Novi, MI)…”

 

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  • Tags: Human Plasma, Pooled Human Plasma Apheresis Derived

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