Single Donor Immunoglobulin G (IgG) Depleted Human Serum

Single Donor Immunoglobulin G (IgG) Depleted Human Serum is whole blood derived. The whole blood is collected from donors in an FDA-approved collection center. The blood is allowed to clot and is then processed into serum. IgG depletion is achieved through the use of immobilized Protein A.

This product is offered by the vial, with typical finished volumes of between 30 and 40mL per vial. If you have custom volume and/or aliquot requests, please let us know prior to placing your order. 

Viral Testing
Each unit is tested for the standard FDA-required viral markers, and found negative for HBsAg, HCV, HIV-1/HIV-2 Antigen Antibody Combo, and Anti‑T. Pallidum using FDA-approved methods using FDA-approved methods. When applicable a licensed NAT for Babesia has been performed and found to be non-reactive, if you would like any further testing or analysis performed prior to shipping, please let us know. While we make every effort to ensure the safety of our products, we recommend following universal precautions as laid out the following organizations WHO, CDC and OSHA, handle biological materials as if capable of spreading infectious disease.

• Preheat a water bath to 37 C.
• Place the frozen plasma sample directly in the water bath.
• Gently agitate the plasma sample every 5-10 minutes to insure even thawing.
• The total thawing time will depend on the frozen sample volume. A 10 ml sample might be thawed completely in 5 minutes, but a large sample could take up to 1 hour.
• The thawed sample should be used immediately or stored at 4 C for up to 24 hours. Liquid plasma should never be kept on ice or stored below 0 C as the cold may cause clotting.
• Plasma should be visually inspected for signs of clotting or precipitation before use in experiments. A coagulation test such as aPTT can also be performed to verify the preservation of the hemostasis system.
• Plasma should always be snap-frozen by placing the tube in dry ice for at least 1 hour. Large containers can be covered in dry ice for even freezing.
• Frozen plasma should be stored at –20 C or colder. Lower temperatures will help preserve labile plasma proteins for longer time periods.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

Please be aware the image pictured is for illustrative purposes only, and your product packaging and appearance may vary.