SARS-CoV-2 (COVID-19) NSP8 Recombinant Protein N-His Tag Lyophilized

SARS-CoV-2 (COVID-19) NSP8 Recombinant Protein N-His Tag Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in Supplied as lyophilized from PBS, pH7.5 with a purity of >85% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining..

More Details:

• Species: SARS-CoV-2
• Target:
• Purity: >85% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining.
• Source: E. coli
• Storage Conditions: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Additional Information:

Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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