Rat Progranulin Recombinant Protein DDDDK Tag Lyophilized

Rat Progranulin Recombinant Protein DDDDK Tag Lyophilized from Innovative Research has been recombinantly produced in HEK293 cells. This is a Lyophilized protein buffered in Lyophilized from 0.2um-filtered solution in PBS. with a purity of >95% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ and#956;g purified protein (LAL test; Lonza)..

More Details:

• Species: Rat
• Target: Grn
• Purity: >95% (SDS-PAGE).
  
  Endotoxin level is less than 0.1EU/ and#956;g purified protein (LAL test; Lonza).
• Source: HEK293 cells
• Storage Conditions: Stable for at least 1 year after receipt when stored at -20°C.

Additional Information:

Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer‘s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.

This recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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