Rabbit Anti RB1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Immunofluorescence)IRBAMLRB1AP819120UL
Rabbit Anti RB1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Immunofluorescence) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been affinity purified.
- Host: Rabbit
- Species: Human,Mouse
- Target: RB1
- Clonality: Polyclonal
- Purity: Affinity Purified
- Immunogen: Recombinant fusion protein of human Rb (NP_000312.2).
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
This product can be used in analytical tools such as Immunofluorescence.
At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
For research use only.
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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