Rabbit Anti PRPS1 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)IRBAMLPRPS1AP944120UL
Rabbit Anti PRPS1 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% sodium azide and 50% glycerol, pH7.4 This antibody has been affinity purified.
- Host: Rabbit
- Species: Human,Mouse
- Target: PRPS1
- Clonality: Polyclonal
- Purity: Affinity Purified
- Immunogen: Synthetic peptide of human PRPS1/2/1L1
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
PRPS (phosphoribosyl pyrophosphate synthetase) proteins catalyze the synthesis of phosphoribosyl pyrophosphate (PRPP). Three human PRPS isoforms exist and are encoded by three different genes. PRPS1 and PRPS2 (also known as PRS1 and PRS2, respectively) are ubiquitously expressed, while PRPS3 (also known as PRPS1L1) is specific to the testis. PRPP is an important substrate synthesized from MgATP and ribose-5-phosphate in a reaction that requires inorganic phosphate and magnesium as a cofactor. PRPP is essential in the synthesis of nearly all nucleotides, implying that PRPS1/2 play an important role in nucleotide biosynthesis and purine metabolism. A mutation in the gene encoding PRPS1 may result in PRPS superactivity, a disease characterized by gout and the overproduction of purine nucleotides, uric acid and PRPP. PRPS1 mutations can also lead to a reduction in PRPS1 activity resulting in ARTS syndrome or CMTX5 (Charcot-Marie-Tooth disease X-linked recessive type 5).
This product can be used in analytical tools such as Western Blot,IHC,ELISA.
At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
For research use only.
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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