Rabbit Anti Mouse COL18A1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

Rabbit Anti Mouse COL18A1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

IRBAMSCOL18A1AP082120UL

Innovative Research

  • $247.00


Rabbit Anti Mouse COL18A1 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been affinity purified.

More Details:

  • Host: Rabbit
  • Species: Mouse
  • Target: COL18A1
  • Clonality: Polyclonal
  • Purity: Affinity Purified
  • Immunogen: A synthetic peptide of human COL18A1 (NP_085059.2).
  • Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.

This product can be used in analytical tools such as Western Blot.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.

Product References
Product Disclaimer

This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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