Rabbit Anti MAPK9 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA)IRBAMLMAPK9AP735120UL
Rabbit Anti MAPK9 Polyclonal Affinity Purified (PBS with 0.05% sodium azide and 50% glycerol, pH7.4) (Western Blot,IHC,ELISA) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% sodium azide and 50% glycerol, pH7.4 This antibody has been affinity purified.
- Host: Rabbit
- Species: Human ,Mouse ,Rat
- Target: MAPK9
- Clonality: Polyclonal
- Purity: Affinity Purified
- Immunogen: Synthetic peptide of human MAPK9
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
This product can be used in analytical tools such as Western Blot,IHC,ELISA.
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For research use only.
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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