Rabbit Anti Human PRNP Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA)

Rabbit Anti Human PRNP Polyclonal Antigen Affinity Purified (PBS with 0.05% sodium azide and 40% Glycerol, pH7.4) (IHC,ELISA) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% sodium azide and 40% Glycerol, pH7.4 This antibody has been purified using Antigen Affinity Purified.

More Details:

• Host: Rabbit
• Species: Human, Mouse, Rat
• Target: PRNP
• Clonality: Polyclonal
• Purity: Antigen Affinity Purified
• Immunogen: Fusion protein of human PRNP
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.

This product can be used in analytical tools such as IHC,ELISA.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.