Rabbit Anti Human GSK3 alpha/beta Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4) (Western Blot,IHC-p,Sandwich ELISA) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4 This antibody has been purified using Affinity Purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse,Rat
• Target: GSK3 alpha/beta
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Synthesized peptide derived from human GSK3?/? around the non-phosphorylation site of Tyr279/216.
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin. GSK-3 is a ubiquitously expressed serine/threonine protein kinase that phosphorylates and inactivates glycogen synthase. GSK-3 is a critical downstream element of the PI3 kinase/Akt cell survival pathway whose activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3A and Ser9 of GSK-3BGSK-3 has been implicated in the regulation of cell fate in Dictyostelium and is a component of the Wnt signaling pathway required for Drosophila, Xenopus and mammalian development. GSK-3 has been shown to regulate cyclin D1 proteolysis and subcellular localization.

This product can be used in analytical tools such as Western Blot,IHC-p,Sandwich ELISA.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.

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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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