Rabbit Anti Human CCNE1 Polyclonal Antigen affinity Purified (PBS with 0.05% NaN3 and 40% Glycerol, pH7.4) (IHC,Sandwich ELISA) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 This antibody has been antigen affinity purified.
More Details:
-
Host: Rabbit
-
Species: Human
-
Target: CCNE1
-
Clonality: Polyclonal
-
Purity: Antigen affinity Purified
-
Immunogen: Synthetic peptide of human CCNE1
-
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB.
This product can be used in analytical tools such as IHC,Sandwich ELISA.
At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
For research use only.
Click here to view a video tutorial covering frequently asked questions regarding ELISA workflows.
Powered by Bioz
