Rabbit Anti Human AMPK alpha1/2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4) (Western Blot,IHC-p,Sandwich ELISA) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH 7.4 This antibody has been purified using Affinity Purified.

More Details:

• Host: Rabbit
• Species: Human,Mouse,Rat,Monkey
• Target: AMPK alpha1/2
• Clonality: Polyclonal
• Purity: Affinity Purified
• Immunogen: Synthesized peptide derived from human AMPK?1/2 around the non-phosphorylation site of Thr183/172.
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic A subunit and regulatory B and G subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.

This product can be used in analytical tools such as Western Blot,IHC-p,Sandwich ELISA.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.

Click here to view a video tutorial covering frequently asked questions regarding ELISA workflows.

View all citations/references for Antibodies

View all citations and product references

This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

Please be aware the image pictured is for illustrative purposes only, and your product packaging and appearance may vary.

No Data Sheets available