Rabbit Anti CAPN6 Polyclonal Antigen affinity Purified (PBS with 0.05% NaN3 and 40% Glycerol, pH7.4) (Western Blot,ELISA)

Rabbit Anti CAPN6 Polyclonal Antigen affinity Purified (PBS with 0.05% NaN3 and 40% Glycerol, pH7.4) (Western Blot,Sandwich ELISA) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 This antibody has been antigen affinity purified.

More Details:

• Host: Rabbit
• Species: Human, Mouse, Rat
• Target: CAPN6
• Clonality: Polyclonal
• Purity: Antigen affinity Purified
• Immunogen: Fusion protein of human CAPN6
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

This product can be used in analytical tools such as Western Blot,Sandwich ELISA.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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