Porcine Deoxyribonuclease Purified

Porcine Deoxyribonuclease Purified


Innovative Research

  • $107.00

Porcine Deoxyribonuclease Purified from Innovative Research is a liquid in 50% glycerol. This is a liquid with a concentration of 12,000 units/mg protein.

Deoxyribonuclease II from porcine spleen has a molecular weight of 38 kDa. The enzyme is a glycoprotein endonuclease with trimeric structure. Optimum pH range is 4.5-5.0 at ionic strength 0.15 M. Deoxyribonuclease II (Acid DNase) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA yielding products with 3’-phosphates. It also acts on p-nitrophenylphosphodiesters at pH 5.6-5.9. Bernardi, Biochem. Biophys. Res. Comm., 17, 573 (1971) describes a three stage degradation of native DNA by DNase II. One unit causes an increase in absorbance at 260 nm of 0.001 per minute at 25°C, pH 4.6 using highly polymerized DNA as substrate.

More Details:

  • Source: Porcine Spleen
  • Purification: Chromatographically prepared
  • Storage Conditions: -20°C

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These products are supplied for manufacturing, research and laboratory use only. Researchers and laboratory personnel intending to use any of these products for medical investigation on humans are solely responsible for such use and for compliance with the pertinent regulations of the United States Food and Drug Administration (US-FDA) and other regulations. We do not assume liability for damages resulting from the handling, use and/or disposal of these products, from their use in violation of patent or other rights or reliance upon this information.

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