Pooled Human AB Serum Plasma Derived and Heat Inactivated from Innovative Research is collected from male donors with blood type AB. The plasma (collected via apheresis) is processed into serum at FDA-licensed facilities located in the United States. Our Pooled Human AB Serum is filtered and cell culture tested for mycoplasma, endotoxin, and sterility. The serum then undergoes a heat inactivation process to destroy complement activity. This product is suitable for use in cell culture applications.
Looking for a Heat Inactivated and Gamma Irradiated version of this product? Find it here
Viral Testing
Each unit is tested for the standard FDA-required viral markers, and found negative for HBsAg, HCV, HIV-1, HIV-2, HIV-1Ag or HIV-1 NAT, ALT, West Nile Virus NAT, Zika NAT and syphilis using FDA-approved methods. When applicable a licensed NAT for Babesia has been performed and found to be non-reactive, if you would like any further testing or analysis performed prior to shipping, please let us know. While we make every effort to ensure the safety of our products, we recommend following universal precautions as laid out the following organizations WHO, CDC and OSHA, handle biological materials as if capable of spreading infectious disease.
Please note - this product replaces our old product number IPLA-SERAB-HI, Pooled Normal Human AB Serum Heat Inactivated (same product, new number).
Curious About The Best Way To Thaw Plasma?
- Preheat a water bath to 37 C.
- Place the frozen plasma sample directly in the water bath.
- Gently agitate the plasma sample every 5-10 minutes to insure even thawing.
- The total thawing time will depend on the frozen sample volume. A 10 ml sample might be thawed completely in 5 minutes, but a large sample could take up to 1 hour.
- The thawed sample should be used immediately or stored at 4 C for up to 24 hours. Liquid plasma should never be kept on ice or stored below 0 C as the cold may cause clotting.
- Plasma should be visually inspected for signs of clotting or precipitation before use in experiments. A coagulation test such as aPTT can also be performed to verify the preservation of the hemostasis system.
- Plasma should always be snap-frozen by placing the tube in dry ice for at least 1 hour. Large containers can be covered in dry ice for even freezing.
- Frozen plasma should be stored at –20 C or colder. Lower temperatures will help preserve labile plasma proteins for longer time periods.
This protocol is applicable for plasma containing any anticoagulant of both human and animal origin. While handling serum does not involve the same risk of clotting due to improper handling, we recommend following the above instructions for both plasma and serum for best results
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