Mouse tPA Recombinant Non-Enzymatic Non-Cleavable
Mouse tPA Recombinant Non-Enzymatic Non-Cleavable from Innovative Research has been recombinantly produced in insect cells and purified using affinity chromatography. This is a frozen liquid buffered in 0.4M HEPES; 0.1M NaCl; pH 7.4, with a concentration of 2.0 mg/ml and a purity of >95%.
This product is useful as a positive control for ELISA and western blot and for a variety of in vitro applications including cell differentiation, cell signaling, clotting assays, fibrinolysis, plasminogen activation, protein-protein interactions, receptor binding, thromboelastography, and thrombolysis. Mouse tPA with a double mutation that is permanently single chain and lacks catalytic activity. The non-catalytic mutation site is S481A on the mature protein and S510A on the complete mRNA sequence (UniProtKB: locus TPA_MOUSE, accession P11214). The non-cleavable mutation site is 279E on the mature protein and R308E on the complete mRNA sequence (UniProtKB: locus TPA_MOUSE, accession P11214).
- Source: Insect Cell Culture
- Purification: Affinity purified
- Purity: >95%
- Storage Conditions: -70 C
At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
Please note – this product replaces our old product number IMTPA-ALANC (same product, new number).