Select this product for Molecular Innovations name, Non-enzymatic Mouse tPA and product number, MTPA-S481A. Mouse tPA Recombinant Non-Enzymatic from Innovative Research has been recombinantly produced in insect cells and purified using affinity chromatography. This is a frozen liquid buffered in 0.4M HEPES; 0.1M NaCl; pH 7.4 and a purity of >95%. This product is useful as a positive control for ELISA and western blot and for a variety of in vitro applications including cell differentiation, cell signaling, clotting assays, fibrinolysis, plasminogen activation, protein-protein interactions, receptor binding, thromboelastography, and thrombolysis. This single chain mouse tPA has the active site serine mutated to alanine rendering the enzyme catalytically inactive. The mutation site is S481A on the mature protein and S510A on the complete mRNA sequence (UniProtKB: locus TPA_MOUSE, accession P11214). The tPA still retains exosite binding as well as other biological properties of tPA including but not limited to surface binding to fibrin. More Details: Source: Insect Cell Culture Purification: Affinity purified Purity: >95% Storage Conditions: -70C At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results. Please note ŌĆō this product replaces our old product number IMTPA-S481A (same product, new number).

This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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