Mouse Anti Human IDE Monoclonal Clone 1H4 from Innovative Research is a monoclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide and 50% glycerol pH 7.4. This antibody has been purified using Protein A purification.

More Details:

• Host: Mouse
• Species: Human
• Target: IDE
• Clonality: Monoclonal
• Immunogen: Synthetic Peptide
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.

This product can be used in analytical tools such as Western Blot,IHC-p,Immunofluorescence.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.

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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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