Mouse Anti Human CASP3 Monoclonal Clone 4B8 from Innovative Research is a monoclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 This antibody has been purified using Protein A purification.

More Details:

• Host: Mouse
• Species: Human,Mouse,Rat
• Target: CASP3
• Clonality: Monoclonal
• Immunogen: Synthetic Peptide of Caspase-3
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.

This product can be used in analytical tools such as IHC-p.

At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

For research use only.

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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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