*Miropin Protease Inhibitor

Select this product for Molecular Innovations name, Miropin (Tannerella forsythia serine protease inhibitor) and product number, MIRO-HIS

Miropin Protease Inhibitor from Innovative Research is a prokaryotic serpin (SErine Protease INhibitor) protein from Tannerella forsythia, a human pathogen involved in the pathogenesis of periodontitis. Miropin can inhibit the activity of a broad range of proteases including trypsin, cathepsin G, neutrophil and pancreatic elastases. Therefore, miropin is a unique serpin in its wide range of inhibitory activity. Recombinantly produced in insect cell culture and purified by chelated metal affinity chromatography. Contains a 8X-Histidine tag at the N terminus for purification. This recombinant miropin inhibits the activity of human neutrophil elastase in vitro. At least 95% pure as determined by SDS-PAGE.

More Details:

• Source: Insect Cells
• Gene ID: 34759867
• Species: T. forsythia
• Swiss-Prot/UniProt ID: G8UQY8
• Storage: -70C for up to 12 months
  

References:
1. Ksiazek, M., Mizgalska, D., Enghild, J.J., Scavenius, C.,Thogersen, I.B., and Potempa, J. Miropin, a Novel Bacterial Serpin from the Periodontopathogen Tannerella forsythia, Inhibits a Broad Range of Proteases by Using Different Peptide Bonds within the Reactive Center Loop. (2015) J. Biol. Chem. 290: 658-670.

Select this product for Molecular Innovations name, Miropin (Tannerella forsythia serine protease inhibitor) and product number, MIRO-HIS

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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