Select this product for Molecular Innovations name, Human RAP Stable Mutant and product number, RAP-SM.Human Receptor-Associated Protein (RAP) Recombinant Stable Mutant from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography.

This is a Frozen liquid buffered in 0.1M Tris HCl; 0.15M NaCl; pH 7.4 (Please note: buffer was previously 0.02M HEPES; 0.15M NaCl; 0.001M CaCl2; pH 7.5 and was changed as of May 5, 2025) and a purity of >95% as determined by SDS-PAGE. More Details: Species: Human Target: Receptor-Associated Protein Purification Method: Affinity purified Purity: >95% as determined by SDS-PAGE Analysis Source: E. coli Storage Conditions: -70 C

Additional Information:

Six mutations were made in the D3 domain (Y260 & T297 changed to cystines, generating a novel disulfide bond between helices 2 & 3; H257, H259, H268, & H290 changed to phenylalines). This is a stable mutuant that is resistent to both pH and heat-induced denaturation. This mutant will not unfold at pH 5.5, has a melting temperature of 73C, and is more resistant to trypsin- and chymotrypsin-mediated proteolysis. This product can be used as a control in applications like ELISA and Western Blot. It can be used for a wide range of in vitro applications, including blocking, cell binding, cell differentiation, cell signaling, protein-protein interactions, receptor binding, and more. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

View all citations and product references

This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

Please be aware the image pictured is for illustrative purposes only, and your product packaging and appearance may vary.

No Data Sheets available