*Human Pai 1 Recombinant Stable Mutant P1 Nbd Labeled

*Human Pai 1 Recombinant Stable Mutant P1 Nbd Labeled


Innovative Research

  • $741.00

Select this product for Molecular Innovations name, Human PAI-1 Stable Mutant NBD labeled at P1' of the reactive center loop and product number, CPAI-P1NBD.

Human PAI-1 Recombinant Stable Mutant P1-NBD Labeled from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography. This is a Frozen liquid buffered in 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 with a concentration of 2.5 mg/ml and a purity of >95% as determined by SDS-PAGE.

More Details:

  • Species: Human
  • Target: PAI-1
  • Purification Method: Affinity purified
  • Purity: >95% as determined by SDS-PAGE Analysis
  • Source: E. coli
  • Storage Conditions: -70 C

Additional Information:
Human PAI-1 has four mutations (K154T, Q319L, M354I and N150H) that combine to create stability in the labile molecule, "locking" it to its active conformation. This product modifes the stable mutant through mutagenesis of the P1' methionine residue (Met347) at the P1-P1' sissile bond to cysteine, followed by NBD labeling, to produce a reporter PAI-1 with an extended half life.

This product can be used as a control in applications like ELISA and Western Blot. It can be used for a wide range of in vitro applications, including affinity purification, blocking, fibrinolysis, hypertension studies, inhibition, plasminogen activation, protein-protein interactions, receptor binding, and more. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

Product References
Product Disclaimer

These products are supplied for manufacturing, research and laboratory use only. Researchers and laboratory personnel intending to use any of these products for medical investigation on humans are solely responsible for such use and for compliance with the pertinent regulations of the United States Food and Drug Administration (US-FDA) and other regulations. We do not assume liability for damages resulting from the handling, use and/or disposal of these products, from their use in violation of patent or other rights or reliance upon this information.

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