*Human Pai 1 Recombinant Stable Mutant N Terminal Mutation Substrate

*Human Pai 1 Recombinant Stable Mutant N Terminal Mutation Substrate


Innovative Research

  • $812.00

Select this product for Molecular Innovations name, N-Terminal Cysteine Stable Mutant Substrate Mutant and product number, NTCYSCPAI-T333R.

Human PAI-1 Recombinant Stable Mutant N Terminal Mutation Substrate from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography. This is a Frozen liquid buffered in 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; 1mM DTT; pH 6.6 with a concentration of 2.5 mg/ml and a purity of >95% as determined by SDS-PAGE.

More Details:

  • Species: Human
  • Target: PAI-1
  • Purification Method: Affinity purified
  • Purity: >95% as determined by SDS-PAGE Analysis
  • Source: E. coli
  • Storage Conditions: -70 C

Additional Information:
N-terminal cystein mutation along with four stabilization mutations. Single subsitution at P14 (in the reactive center loop) produces PAI-1 that functions as a subtrate for proteases rather than as an inhibitor. Supplied in buffer with ImM DTT to prevent dimerization.

This product can be used as a control in applications like ELISA and Western Blot. It can be used in a wide range of in vitro applications, including blocking/inhibition, fibrinolysis, plasminogen activation, receptor binding, in hypertension studies, for protein-protein interactions, and more. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

Product References
Product Disclaimer

These products are supplied for manufacturing, research and laboratory use only. Researchers and laboratory personnel intending to use any of these products for medical investigation on humans are solely responsible for such use and for compliance with the pertinent regulations of the United States Food and Drug Administration (US-FDA) and other regulations. We do not assume liability for damages resulting from the handling, use and/or disposal of these products, from their use in violation of patent or other rights or reliance upon this information.

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