*Human Pai 1 Recombinant Stable Mutant N Terminal Mutation Substrate

Select this product for Molecular Innovations name, N-Terminal Cysteine Stable Mutant Substrate Mutant and product number, NTCYSCPAI-T333R.

Human PAI-1 Recombinant Stable Mutant N Terminal Mutation Substrate from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography. This is a Frozen liquid buffered in 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; 1mM DTT; pH 6.6 with a concentration of 2.5 mg/ml and a purity of >95% as determined by SDS-PAGE.

More Details:

• Species: Human
• Target: PAI-1
• Purification Method: Affinity purified
• Purity: >95% as determined by SDS-PAGE Analysis
• Source: E. coli
• Storage Conditions: -70 C

Additional Information:
N-terminal cystein mutation along with four stabilization mutations. Single subsitution at P14 (in the reactive center loop) produces PAI-1 that functions as a subtrate for proteases rather than as an inhibitor. Supplied in buffer with ImM DTT to prevent dimerization.

This product can be used as a control in applications like ELISA and Western Blot. It can be used in a wide range of in vitro applications, including blocking/inhibition, fibrinolysis, plasminogen activation, receptor binding, in hypertension studies, for protein-protein interactions, and more. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.