Human Pai 1 Recombinant Mutant Neutrophil Elastase Inhibitor

Human Pai 1 Recombinant Mutant Neutrophil Elastase Inhibitor

IHUPAI1RNE500UG

Innovative Research

  • $730.00


Human PAI-1 Recombinant Mutant Neutrophil Elastase Inhibitor from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography. This is a Frozen liquid buffered in 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 with a concentration of 2.5 mg/ml and a purity of >95% as determined by SDS-PAGE.

More Details:

  • Species: Human
  • Target: PAI-1
  • Purification Method: Affinity purified
  • Purity: >95% as determined by SDS-PAGE Analysis
  • Source: E. coli
  • Storage Conditions: -70 C

Additional Information:
Variant of Human PAI-1 with a mutation at the active site, making it specific for neutrophil elastase inhibition (R346V). Additional mutations make it resistant to cleavage (V343A) and increase stability (I91L). This preparation contains low endotoxin (less than 20 EU/mg).

This product can be used as a control in applications like ELISA and Western Blot. It can be used in a wide range of in vitro applications, including blocking/inhibition, fibrinolysis, plasminogen activation, receptor binding, in hypertension studies, for protein-protein interactions, and more. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

Product References
Product Disclaimer

This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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