*Human Pai 1 Recombinant Lrp Binding NegativeIHUPAI1RLRP500UG
Select this product for Molecular Innovations name, PAI-1 mutant - stable, no LRP binding and product number, HPAI-R76E-I91L.
Human PAI-1 Recombinant LRP Binding Negative from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography. This is a Frozen liquid buffered in 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 with a concentration of 2.5 mg/ml and a purity of >95% as determined by SDS-PAGE.
- Species: Human
- Target: PAI-1
- Purification Method: Affinity purified
- Purity: >95% as determined by SDS-PAGE Analysis
- Source: E. coli
- Storage Conditions: -20 C
PAI-1 mutant with subsitution of Glutamic Acid for Arginine at postion 76. This greatly reduces PAI-1 binding to low density lipoprotein receptor-related protein (LRP). An additional mutation (Isoleucine 91 to Leucine) provides increased stability for long-term binding experiments.
This product can be used as a control in applications like ELISA and Western Blot. It can be used in a wide range of in vitro applications, including blocking/inhibition, fibrinolysis, plasminogen activation, receptor binding, in hypertension studies, for protein-protein interactions, and more. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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