Human sIL-4 Receptor alpha Recombinant Protein Lyophilized

Human sIL-4 Receptor alpha Recombinant Protein Lyophilized from Innovative Research has been recombinantly produced in CHO cells. This is a Lyophilized protein buffered in with a purity of ? 95% by SDS-PAGE gel and HPLC analyses..

More Details:

• Species: Human
• Target: IL4R
• Purity: ? 95% by SDS-PAGE gel and HPLC analyses.
• Source: CHO cells
• Storage Conditions: The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Additional Information:

IL-4 can signal through type I and type II receptor complexes, which share a common gamma chain (?c). The type I receptor contains, in addition to the ?c, an IL-4R? subunit, whereas the type II receptor contains the IL-13R?. The secreted extracellular domain of IL-4R?, called sIL-4R?, binds IL-4 and anTagonizes its activity. It plays an important role in regulating the differentiation of naïve CD4+ T cells and class switching to IgG1 and IgE. CHO cell-derived Recombinant Human sIL-4 Receptor ? is a 23.9 kDa glycoprotein corresponding to 209 amino acid residues of the extracellular domain of IL-4R?. As a result of glycosylation, Recombinant Human sIL-4 Receptor ? migrates with an apparent molecular mass of approximately 50-65 kDa by SDS-PAGE gel, under reducing conditions.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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