Human / Mouse FLT3 Ligand Recombinant Protein Fc Tag from Innovative Research has been recombinantly produced in CHO cells. This is a Liquid protein buffered in In PBS (sterile). with a purity of >95% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ and#956;g purified protein (LAL test; Lonza)..

More Details:

• Species: Human, Mouse
• Target: FLT3LG
• Purity: >95% (SDS-PAGE).
  
  Endotoxin level is less than 0.1EU/ and#956;g purified protein (LAL test; Lonza).
• Source: CHO cells
• Storage Conditions: Stable for at least 6 months after receipt when stored at -20°C.

Additional Information:

FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers.

This recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.

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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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