Human MIP-1a Recombinant Protein Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in with a purity of ? 98% by SDS-PAGE gel and HPLC analyses..

More Details:

• Species: Human
• Target: CCL3
• Purity: ? 98% by SDS-PAGE gel and HPLC analyses.
• Source: E. coli
• Storage Conditions: The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Additional Information:

Both MIP-1? and MIP-1? are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1? and MIP-1? exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1? selectively attracting CD8+ lymphocytes, and MIP-1? selectively attracting CD4+ lymphocytes. Additionally, MIP-1? and MIP-1? have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1? and MIP-1? are active on human and murine hematopoietic cells. Recombinant Human MIP-1? is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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